Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 7/20 | 0.51 |
| ▸ | HRH1 | P35367 | 1/20 | 0.45 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.45 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20828384 | 0.78 | RXFP1 (0.47) | MAOBMRGPRX4KDM4EPOLB | |
| SCHEMBL20828525 | 0.75 | RAB9A (0.45) | L3MBTL1CHEK2POLB | |
| SCHEMBL20828380 | 0.74 | CSF1R (0.47) | L3MBTL1 | |
| SCHEMBL30602662 | 0.74 | L3MBTL1 (0.50) | LMNAPKMHSD17B10MAOBL3MBTL1 | |
| SCHEMBL20832626 | 0.74 | L3MBTL1 (0.50) | LMNAPKMHSD17B10MAOBL3MBTL1 | |
| SCHEMBL20828389 | 0.73 | FFAR1 (0.46) | L3MBTL1POLB | |
| SCHEMBL4640143 | 0.70 | MAOB (0.76) | MAOBL3MBTL1MRGPRX4POLB | |
| SCHEMBL31172140 | 0.70 | MAOB (0.76) | MAOBL3MBTL1MRGPRX4POLB | |
| SCHEMBL24968507 | 0.69 | MAOB (0.55) | LMNAPKMHSD17B10MAOBAOC3 | |
| SCHEMBL30152319 | 0.69 | MAOB (0.55) | LMNAPKMHSD17B10MAOBAOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3682881-A1 | COMPOUND HAVING CYCLIC STRUCTURE | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2020-07-22 | — | — | EP | disclosed |