Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | RAF1 | P04049 | 1/20 | 0.45 |
| ▸ | BRAF | P15056 | 1/20 | 0.45 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | PLG | P00747 | 1/20 | 0.43 |
| ▸ | PLAU | P00749 | 1/20 | 0.43 |
| ▸ | PLAT | P00750 | 1/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20828516 | 0.90 | RAB9A (0.50) | FFAR1RAB9ARAF1BRAFMAPK14 | |
| SCHEMBL20828525 | 0.86 | RAB9A (0.45) | FFAR1RAB9ABRAFGAAPTPN1 | |
| SCHEMBL20828529 | 0.84 | HIF1A (0.46) | FFAR1RAB9AHIF1AEPAS1GAA | |
| SCHEMBL20828380 | 0.83 | CSF1R (0.47) | FFAR1RAB9AGAAPLGPLAU | |
| SCHEMBL20828384 | 0.80 | RXFP1 (0.47) | FFAR1MEN1KMT2APOLBRXFP1 | |
| SCHEMBL20828477 | 0.78 | RXFP1 (0.45) | FFAR1RAB9APLAUMAPTTRPV1 | |
| SCHEMBL20828451 | 0.74 | BRAF (0.44) | RAB9ARAF1BRAFMAPK14ROCK2 | |
| SCHEMBL20828481 | 0.74 | FFAR1 (0.45) | FFAR1RAB9ARAF1BRAFMAPK14 | |
| SCHEMBL22237402 | 0.73 | LMNA (0.52) | L3MBTL1POLB | |
| SCHEMBL20828420 | 0.71 | DGAT1 (0.47) | RAB9AGAAROCK2MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019054430-A1 | AMIDE COMPOUND HAVING AROMATIC HETEROCYCLE | 第一三共株式会社 | 2019-03-21 | — | — | WO | disclosed |