Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | PLG | P00747 | 2/20 | 0.42 |
| ▸ | PLAU | P00749 | 2/20 | 0.42 |
| ▸ | PLAT | P00750 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.41 |
| ▸ | BRAF | P15056 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.41 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20828389 | 0.86 | FFAR1 (0.46) | RAB9AGAAFFAR1PTPN1PLG | |
| SCHEMBL20828380 | 0.84 | CSF1R (0.47) | RAB9AGAAFFAR1PLGPLAU | |
| SCHEMBL20828529 | 0.83 | HIF1A (0.46) | RAB9AGAAFFAR1PTPN1MAPT | |
| SCHEMBL20828384 | 0.80 | RXFP1 (0.47) | FFAR1POLBRXFP1 | |
| SCHEMBL20828477 | 0.79 | RXFP1 (0.45) | RAB9AFFAR1PLAUTRPV1MAPT | |
| SCHEMBL20828516 | 0.76 | RAB9A (0.50) | RAB9AGAAFFAR1PTPN1L3MBTL1 | |
| SCHEMBL22237402 | 0.75 | LMNA (0.52) | L3MBTL1POLBCHEK2 | |
| SCHEMBL4970019 | 0.71 | TRPV1 (0.67) | RAB9ATRPV1MAPT | |
| SCHEMBL31395292 | 0.69 | POLB (0.60) | RAB9APTPN1L3MBTL1ALDH1A1POLB | |
| SCHEMBL10316101 | 0.67 | COMT (0.44) | RAB9APOLBTRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019054430-A1 | AMIDE COMPOUND HAVING AROMATIC HETEROCYCLE | 第一三共株式会社 | 2019-03-21 | — | — | WO | disclosed |