Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 2/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | RORC | P51449 | 7/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20832631 | 0.84 | MAOA (0.44) | L3MBTL1PPARGMAOAMAOBRORC | |
| SCHEMBL20828522 | 0.82 | RAB9A (0.43) | L3MBTL1PPARGMAOAMAOBRORC | |
| SCHEMBL20828440 | 0.80 | MAOA (0.42) | L3MBTL1PPARGMAOAMAOBHTR2C | |
| SCHEMBL22227863 | 0.75 | PPARG (0.48) | L3MBTL1PPARGMAOAMAOBHTR2C | |
| SCHEMBL20828381 | 0.73 | RAB9A (0.41) | PPARGRORCMEN1RAB9AKMT2A | |
| SCHEMBL28430362 | 0.73 | RAB9A (0.45) | L3MBTL1PPARGMAOAMAOBRORC | |
| SCHEMBL20832656 | 0.73 | RAB9A (0.45) | L3MBTL1PPARGMAOAMAOBRORC | |
| SCHEMBL20832880 | 0.71 | MAPT (0.46) | PPARGMAOAMAOBRORCMEN1 | |
| SCHEMBL22623097 | 0.71 | L3MBTL1 (0.57) | L3MBTL1PPARGMAOAMAOBHTR2C | |
| SCHEMBL20832811 | 0.69 | L3MBTL1 (0.50) | L3MBTL1PPARGMAOAMAOBHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3682881-A1 | COMPOUND HAVING CYCLIC STRUCTURE | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2020-07-22 | — | — | EP | disclosed |