SCHEMBL22238944

SCHEMBL22238944

CC1OB(c2ccc(-c3nnn(C)n3)nc2)OC1(C)C

nearest known ligand 0.34

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.34
MAOB P27338 1/20 0.34
PPARA Q07869 1/20 0.32
DGAT1 O75907 1/20 0.31
PDE10A Q9Y233 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2147791 0.84 DGAT1 (0.44) MAOAMAOBPPARADGAT1
SCHEMBL29406802 0.84 DGAT1 (0.44) MAOAMAOBPPARADGAT1
SCHEMBL1485062 0.72 DGAT1 (0.34) DGAT1
SCHEMBL14038105 0.70 DGAT1 (0.43) DGAT1
SCHEMBL2100970 0.68
SCHEMBL8117268 0.67 MAOA (0.44) MAOAMAOBPPARAPDE10A
SCHEMBL46305 0.67 CCR1 (0.52) MAOAMAOBPPARAPDE10A
SCHEMBL23576574 0.66 EPHX2 (0.41) MAOAMAOBPPARAPDE10A
SCHEMBL1557876 0.66 MAOA (0.36) MAOAMAOBPPARAPDE10A
SCHEMBL2644959 0.66 MAOA (0.39) MAOAMAOBPPARAPDE10A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3372596-B1 PREPARATION METHOD FOR TEDIZOLID, TEDIZOLID INTERMEDIATE, AND PREPARATION METHOD THEREFOR ZHEJIANG HUAHAI PHARM CO LTD (CN) 2020-07-22 EP disclosed