Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CTSL | P07711 | 2/20 | 0.32 |
| ▸ | CTSB | P07858 | 2/20 | 0.32 |
| ▸ | CTSK | P43235 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | CASP3 | P42574 | 2/20 | 0.31 |
| ▸ | CTSD | P07339 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | CASP7 | P55210 | 1/20 | 0.31 |
| ▸ | CASP9 | P55211 | 1/20 | 0.31 |
| ▸ | CASP6 | P55212 | 1/20 | 0.31 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.31 |
| ▸ | CTSS | P25774 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19706578 | 0.91 | MGLL (0.33) | LMNAMGLLHPGDTERT | |
| SCHEMBL19647083 | 0.83 | KMT2A (0.36) | LMNAKMT2AHPGD | |
| SCHEMBL21416506 | 0.83 | KMT2A (0.36) | LMNAKMT2AHPGD | |
| SCHEMBL19703231 | 0.81 | TERT (0.32) | CA2CA5ALMNAHPGDTERT | |
| SCHEMBL20196463 | 0.80 | APC (0.30) | LMNAMEN1KMT2A | |
| SCHEMBL21841758 | 0.80 | ELANE (0.32) | CA2CA5ALMNAMEN1KMT2A | |
| SCHEMBL21297090 | 0.80 | MGLL (0.36) | LMNAMEN1KMT2AMGLLHPGD | |
| SCHEMBL25776325 | 0.80 | MGLL (0.36) | LMNAMEN1KMT2AMGLLHPGD | |
| SCHEMBL25563513 | 0.80 | KMT2A (0.36) | LMNAMEN1KMT2AMGLLHPGD | |
| SCHEMBL24344744 | 0.79 | CA2 (0.36) | CA2CA5ALMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3525826-B1 | NON-LINEAR SELF-IMMOLATIVE LINKERS AND CONJUGATES THEREOF | BYONDIS BV (NL) | 2020-07-22 | — | — | EP | disclosed |