Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 2/20 | 0.36 |
| ▸ | FEN1 | P39748 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CHKA | P35790 | 1/20 | 0.33 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18654717 | 0.77 | MCHR1 (0.37) | NUDT1 | |
| SCHEMBL10187279 | 0.77 | MCHR1 (0.41) | ALOX5APFEN1CA2CHKANUDT1 | |
| SCHEMBL17778782 | 0.76 | FEN1 (0.32) | ALOX5APFEN1 | |
| SCHEMBL20172295 | 0.75 | TSHR (0.41) | — | |
| SCHEMBL7489421 | 0.74 | THRB (0.38) | ALOX5APFEN1CA2CHKA | |
| SCHEMBL16291043 | 0.74 | MAPT (0.38) | ALOX5APFEN1CA2CHKA | |
| SCHEMBL18654366 | 0.74 | NUDT1 (0.44) | NUDT1 | |
| SCHEMBL18654540 | 0.74 | CDK2 (0.31) | NUDT1 | |
| SCHEMBL11373823 | 0.73 | PIK3CD (0.37) | ALOX5APFEN1CA2CHKA | |
| SCHEMBL17778688 | 0.72 | KDM4E (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3221317-B1 | SUBSTITUTED BRIDGED UREA ANALOGS AS SIRTUIN MODULATORS | GLAXOSMITHKLINE IP NO 2 LTD (GB) | 2020-07-22 | — | — | EP | disclosed |