Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22240292 | 0.90 | MEN1 (0.32) | TRPV1CNR1CNR2 | |
| SCHEMBL22240215 | 0.90 | NOS2 (0.32) | — | |
| SCHEMBL22240057 | 0.87 | MEN1 (0.34) | — | |
| SCHEMBL22240059 | 0.86 | AXL (0.31) | — | |
| SCHEMBL22240073 | 0.84 | HTT (0.34) | — | |
| SCHEMBL19714367 | 0.84 | CNR2 (0.38) | TRPV1CNR1CNR2 | |
| SCHEMBL19714486 | 0.84 | CNR2 (0.38) | TRPV1CNR1CNR2 | |
| SCHEMBL19713805 | 0.84 | CNR2 (0.38) | TRPV1CNR1CNR2 | |
| SCHEMBL19736435 | 0.84 | CNR2 (0.38) | TRPV1CNR1CNR2 | |
| SCHEMBL22239854 | 0.84 | CHI3L1 (0.33) | CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3221317-B1 | SUBSTITUTED BRIDGED UREA ANALOGS AS SIRTUIN MODULATORS | GLAXOSMITHKLINE IP NO 2 LTD (GB) | 2020-07-22 | — | — | EP | disclosed |