SCHEMBL2223994

SCHEMBL2223994

FC(F)(F)CC(F)(F)C(F)(F)OCc1cc(CCl)ccc1-c1ccccc1

nearest known ligand 0.38

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TACR1 P25103 3/20 0.38
FFAR1 O14842 3/20 0.35
FFAR4 Q5NUL3 3/20 0.35
CSNK2A1 P68400 2/20 0.33
ALOX5 P09917 1/20 0.31
RXRA P19793 1/20 0.31
RXRB P28702 1/20 0.31
RXRG P48443 1/20 0.31
GSTP1 P09211 1/20 0.30
TTR P02766 1/20 0.30
CHRM5 P08912 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL769993 0.75 IDO1 (0.33)
SCHEMBL29712512 0.74 CSNK2A1 (0.46) TACR1FFAR1FFAR4CSNK2A1ALOX5
SCHEMBL2223984 0.69 TACR1 (0.38) TACR1FFAR1FFAR4ALOX5
SCHEMBL3903655 0.68 HCRTR1 (0.42) FFAR1FFAR4CSNK2A1RXRARXRB
SCHEMBL11368554 0.67 ALOX5 (0.55) CSNK2A1ALOX5TTR
SCHEMBL28035133 0.66 PTGS1 (0.49) FFAR1FFAR4RXRARXRB
SCHEMBL2223979 0.66 KIF11 (0.41) RXRARXRBRXRG
SCHEMBL2223991 0.66 TACR1 (0.37) TACR1FFAR1FFAR4ALOX5
SCHEMBL4345051 0.64 CSNK2A1 (0.42) FFAR1FFAR4CSNK2A1GSTP1TTR
SCHEMBL3912942 0.64 CSNK2A1 (0.70) CSNK2A1TTR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2516389-A1 FLUORINATED ARYLENE-CONTAINING COMPOUNDS, METHODS, AND POLYMERS PREPARED THEREFROM 3M Innovative Properties Company (US) 2012-10-31 EP disclosed
WO-2011087717-A1 FLUORINATED ARYLENE-CONTAINING COMPOUNDS, METHODS, AND POLYMERS PREPARED THEREFROM 3M INNOVATIVE PROPERTIES COMPANY (US) 2011-07-21 WO disclosed