SCHEMBL2224

SCHEMBL2224

O=[C]Cc1ccccc1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28377926 0.97 CALM1 (0.50)
SCHEMBL29073219 0.97 CALM1 (0.50)
SCHEMBL1271150 0.85 TAAR1 (0.50)
SCHEMBL11139354 0.84 CYP3A4 (0.42)
SCHEMBL28331340 0.81 CALM1 (0.52)
SCHEMBL6895272 0.80 MEN1 (0.41)
SCHEMBL6805048 0.79 LMNA (0.58)
SCHEMBL7123532 0.79 LTA4H (0.55)
SCHEMBL6620513 0.79 AGXT (0.50)
SCHEMBL4417702 0.78 CALM1 (0.41)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 38908 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4399212-A1 SUBSTITUTED 2,3-DIHYDRO[1,3]THIAZOLO[4,5-B]PYRIDINES, SALTS THEREOF AND THEIR USE AS HERBICIDALLY ACTIVE SUBSTANCES Bayer Aktiengesellschaft (DE) 2024-07-17 EP claimed
US-12018021-B2 Thiophene derivatives for the treatment of disorders caused by IgE UCB Biopharma SRL (BE) 2024-06-25 US claimed
CN-118159542-A Substituted 2, 3-dihydro [1,3] thiazolo [4,5-b ] pyridines, salts thereof and their use as herbicidal agents 拜耳公司 2024-06-07 CN claimed
EP-4376830-A1 USE OF SGLT-2 INHIBITORS FOR THE PREVENTION AND/OR TREATMENT OF RENAL DISEASES IN NON-HUMAN MAMMALS Boehringer Ingelheim Vetmedica GmbH (DE) 2024-06-05 EP claimed
EP-4376819-A1 USE OF SGLT-2 INHIBITORS FOR THE PREVENTION AND/OR TREATMENT OF HYPERTENSION IN NON-HUMAN MAMMALS Boehringer Ingelheim Vetmedica GmbH (DE) 2024-06-05 EP claimed
EP-4376829-A1 USE OF SGLT-2 INHIBITORS FOR THE PREVENTION AND/OR TREATMENT OF CARDIAC DISEASES IN NON-HUMAN MAMMALS EXCLUDING FELINES, IN PARTICULAR CANINES Boehringer Ingelheim Vetmedica GmbH (DE) 2024-06-05 EP claimed
CN-118125950-A Chiral alpha-amino acid derivative and preparation method and application thereof 四川大学 2024-06-04 CN claimed
US-20240158441-A1 BRANCHED PEPTIDES FOR ENZYMATIC ASSEMBLY AND MITOCHONDRIA DRUG DELIVERY NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2024-05-16 US claimed
CN-118021978-A GHRH antagonists for use in methods of treating sarcoidosis 迈阿密大学 2024-05-14 CN claimed
CN-113454147-B Crosslinkable electroactive fluorinated polymers comprising photoactive groups 阿科玛法国公司 2024-05-10 CN claimed
US-3962036-A PROCESS FOR THE MANUFACTURE OF 7-AMINO-CEPHALOSPORANIC ACID-TYPE COMPOUNDS CIBA-GEIGY CORPORATION (US) 1976-06-08 US claimed
US-3962209-A PROCESS FOR PREPARING AZO DYESTUFFS WITH ORTHO-AZO CYANO GROUPS BY CYANO EXCHANGE OF METAL CYANIDES AND HALO DYESTUFFS BAYER AKTIENGESELLSCHAFT (DT) 1976-06-08 US claimed
US-3953437-A Process of preparing cephalosporanic acid ester derivatives YAMANOUCHI PHARMACEUTICAL CO., LTD. (JA) 1976-04-27 US claimed
US-3953596-A 8-Oxa-3-azabicyclo(3.2.1)octane analgesic compositions and method of alleviating pain in animals ICI UNITED STATES INC. (US) 1976-04-27 US claimed
US-3944545-A Process for preparing desacetoxycephalosporins ELI LILLY AND COMPANY (US) 1976-03-16 US claimed
US-3941779-A Method for producing 2-(substituted thio)-3-cephem derivatives E. R. SQUIBB & SONS, INC. (US) 1976-03-02 US claimed
US-3936303-A Photographic photosensitive element and developing method thereof FUJI PHOTO FILM CO., LTD. (JA) 1976-02-03 US claimed
US-3936447-A 7-Acylamino-desacetoxy-cephalosporanic acid esters and their production BAYER AKTIENGESELLSCHAFT (DT) 1976-02-03 US claimed
US-3935198-A BY HEATING THE PENICILLIN SULFOXIDE YAMANOUCHI PHARMACEUTICAL CO., LTD. (JA) 1976-01-27 US claimed
US-3932392-A DICYCLOHEXYLAMINE, DIISOPROPYLAMINE BRISTOL-MYERS COMPANY (US) 1976-01-13 US claimed