Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 6/20 | 0.55 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.55 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MMP12 | P39900 | 1/20 | 0.47 |
| ▸ | MMP13 | P45452 | 1/20 | 0.47 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.47 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.45 |
| ▸ | BAX | Q07812 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6799652 | 0.80 | APP (0.58) | FFAR1MAOAFFAR4 | |
| SCHEMBL23098203 | 0.80 | SRD5A2 (0.70) | LTA4HSRD5A2FFAR1TSHRPLA2G2A | |
| SCHEMBL9906839 | 0.80 | SRD5A2 (0.70) | LTA4HSRD5A2FFAR1TSHRPLA2G2A | |
| SCHEMBL2224 | 0.79 | — | — | |
| SCHEMBL6643438 | 0.79 | LTA4H (0.55) | LTA4HSRD5A2FFAR1TSHRPLA2G2A | |
| SCHEMBL625835 | 0.79 | LTA4H (0.55) | LTA4HSRD5A2FFAR1TSHRPLA2G2A | |
| SCHEMBL6805048 | 0.79 | LMNA (0.58) | LTA4HSRD5A2FFAR1MAOAFFAR4 | |
| SCHEMBL10269397 | 0.78 | SRD5A2 (0.68) | LTA4HSRD5A2FFAR1TSHRNR1H2 | |
| SCHEMBL29073219 | 0.77 | CALM1 (0.50) | TSHRPLA2G2A | |
| SCHEMBL28377926 | 0.77 | CALM1 (0.50) | FFAR1TSHRFFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015116968-A1 | COMPOSITIONS AND METHODS FOR MODULATING HEXIM1 EXPRESSION | CASE WESTERN RESERVE UNIVERSITY (US) | 2015-08-06 | — | — | WO | disclosed |
| EP-1472208-A1 | NOVEL 3-ARYL-2,5-DIHYDROXY-1,4-BENZOQUINONE DERIVATIVES, THEIR PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | LES LABORATOIRES SERVIER (FR) | 2004-11-03 | — | — | EP | disclosed |
| CN-1153765-C | 4-aryl-1-phenylalkyl-1, 2,3, 6-tetrahydropyridines having neurotrophic and protective activity | ��ŵ�Ѻϳ�ʵ���� | 2004-06-16 | — | — | CN | disclosed |
| WO-2003066561-A1 | NOVEL 3-ARYL-2,5-DIHYDROXY-1,4-BENZOQUINONE DERIVATIVES, THEIR PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | LES LABORATOIRES SERVIER (FR) | 2003-08-14 | — | — | WO | disclosed |
| CN-1189154-A | 4-aryl-1-phenylalkyl-1,2,3,6-Tetrahydropyridines having neurotrophic and neuroprotective activity | SANOFI SA (FR) | 1998-07-29 | — | — | CN | disclosed |