SCHEMBL2224015

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2224849	0.93	CYP3A4 (0.43)	CYP3A4CYP2D6DRD2SLC6A2HTR2A
	SCHEMBL2221872	0.90	KCNH2 (0.42)	CYP3A4KCNH2CDK7CCNHMNAT1
	SCHEMBL2222683	0.88	CYP3A4 (0.44)	CYP3A4CYP2D6DRD2SLC6A2HTR2A
	SCHEMBL2220948	0.88	MAPT (0.41)	CYP3A4CYP2D6DRD2SLC6A2HTR2A
	Hydrochloric Acid SCHEMBL2224877	0.87	CYP3A4 (0.43)	CYP3A4CYP2D6DRD2SLC6A2HTR2A
	SCHEMBL2224793	0.87	CYP3A4 (0.47)	CYP3A4CYP2D6DRD2SLC6A2HTR2A
	SCHEMBL2224629	0.87	CYP3A4 (0.47)	CYP3A4CYP2D6DRD2SLC6A2HTR2A
	SCHEMBL14354338	0.85	CYP3A4 (0.58)	CYP3A4CYP2D6DRD2SLC6A2HTR2A
	SCHEMBL2222595	0.83	MAPT (0.50)	CYP3A4CYP2D6DRD2SLC6A2HTR2A
	Cadaverine Tartrate SCHEMBL2223690	0.81	CYP3A4 (0.50)	CYP3A4CYP2D6DRD2SLC6A2HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.