Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 2/20 | 0.55 |
| ▸ | CETP | P11597 | 2/20 | 0.42 |
| ▸ | EGFR | P00533 | 2/20 | 0.35 |
| ▸ | BTK | Q06187 | 2/20 | 0.35 |
| ▸ | P2RY14 | Q15391 | 2/20 | 0.35 |
| ▸ | ATR | Q13535 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RXRA | P19793 | 2/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.34 |
| ▸ | F10 | P00742 | 1/20 | 0.34 |
| ▸ | ACACB | O00763 | 1/20 | 0.34 |
| ▸ | KIT | P10721 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | LIPE | Q05469 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2224272 | 0.88 | S1PR1 (0.55) | S1PR1CETPEGFRBTKMAPT | |
| SCHEMBL2224650 | 0.88 | S1PR1 (0.58) | S1PR1MAPT | |
| SCHEMBL2228933 | 0.87 | S1PR1 (0.58) | S1PR1CETPEGFRBTKACACB | |
| SCHEMBL14797047 | 0.86 | S1PR1 (0.77) | S1PR1CETPP2RY14PPARG | |
| SCHEMBL2224909 | 0.85 | S1PR1 (0.58) | S1PR1MAPT | |
| SCHEMBL2223355 | 0.85 | S1PR1 (0.73) | S1PR1 | |
| SCHEMBL2223974 | 0.83 | S1PR1 (0.49) | S1PR1CETPMAPTPPARG | |
| SCHEMBL2269044 | 0.83 | S1PR1 (0.55) | S1PR1MAPTACACB | |
| SCHEMBL2223341 | 0.82 | S1PR1 (0.54) | S1PR1GRIN1GRIN2BPPARG | |
| SCHEMBL2225909 | 0.82 | S1PR1 (0.54) | S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2523962-A1 | CARBOXYLIC ACID DERIVATIVES HAVING A 2,5-SUBSTITUTED OXAZOLOPYRIMIDINE RING | SANOFI (FR) | 2012-11-21 | — | — | EP | disclosed |
| WO-2011086079-A1 | CARBOXYLIC ACID DERIVATIVES HAVING A 2,5-SUBSTITUTED OXAZOLOPYRIMIDINE RING | SANOFI-AVENTIS (FR) | 2011-07-21 | — | — | WO | disclosed |