Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 8/20 | 0.52 |
| ▸ | ALK | Q9UM73 | 6/20 | 0.50 |
| ▸ | AXL | P30530 | 2/20 | 0.45 |
| ▸ | MAPK9 | P45984 | 3/20 | 0.45 |
| ▸ | MAPK10 | P53779 | 3/20 | 0.45 |
| ▸ | CCNA2 | P20248 | 3/20 | 0.43 |
| ▸ | CDK2 | P24941 | 3/20 | 0.43 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.43 |
| ▸ | CCNK | O75909 | 2/20 | 0.43 |
| ▸ | CCND3 | P30281 | 2/20 | 0.43 |
| ▸ | CDK9 | P50750 | 2/20 | 0.43 |
| ▸ | CDK6 | Q00534 | 2/20 | 0.43 |
| ▸ | NEK2 | P51955 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30948623 | 0.94 | EGFR (0.50) | EGFRALKAXLMAPK9MAPK10 | |
| SCHEMBL22246276 | 0.90 | EGFR (0.49) | EGFRALKMAPK9MAPK10CCNA2 | |
| SCHEMBL30948583 | 0.87 | EGFR (0.53) | EGFRALKAXLMAPK9MAPK10 | |
| SCHEMBL30948584 | 0.87 | EGFR (0.53) | EGFRALKAXLMAPK9MAPK10 | |
| SCHEMBL22246255 | 0.87 | EGFR (0.48) | EGFRALKMAPK9MAPK10CCNA2 | |
| SCHEMBL22246151 | 0.86 | EGFR (0.66) | EGFRALK | |
| SCHEMBL29396779 | 0.86 | EGFR (0.66) | EGFRALK | |
| SCHEMBL22246290 | 0.86 | EGFR (0.46) | EGFRALKMAPK9MAPK10CCNA2 | |
| SCHEMBL22246232 | 0.85 | MAPK9 (0.55) | EGFRALKMAPK9MAPK10CCNA2 | |
| SCHEMBL30503703 | 0.85 | MAPK9 (0.55) | EGFRALKAXLMAPK9MAPK10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020147702-A1 | EGFR INHIBITORS, COMPOSITIONS AND METHODS THEREOF | BETTA PHARMACEUTICALS CO., LTD (CN) | 2020-07-23 | — | — | WO | disclosed |