Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SCD | O00767 | 1/20 | 0.36 |
| ▸ | CA5A | P35218 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TGM2 | P21980 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24621692 | 0.82 | TSHR (0.40) | GLASRCMAPK1SMYD3LMNA | |
| SCHEMBL15223688 | 0.79 | L3MBTL1 (0.42) | GLALMNAALDH1A1SCDCA5A | |
| SCHEMBL11910527 | 0.78 | SRC (0.41) | GLASRCMAPK1LMNAALDH1A1 | |
| SCHEMBL17625591 | 0.78 | CA5A (0.41) | GLASMYD3LMNAALDH1A1SCD | |
| SCHEMBL15495572 | 0.77 | SRC (0.36) | GLASRCMAPK1SMYD3LMNA | |
| SCHEMBL18235987 | 0.76 | POLB (0.38) | GLASRCMAPK1LMNAALDH1A1 | |
| SCHEMBL17427978 | 0.75 | DPP4 (0.44) | LMNAALDH1A1 | |
| SCHEMBL8931483 | 0.74 | HRH4 (0.41) | GLASRCLMNAALDH1A1TSHR | |
| SCHEMBL15257805 | 0.74 | MAOA (0.43) | SRCALDH1A1KMT2APOLB | |
| SCHEMBL16891850 | 0.74 | POLB (0.38) | SRCLMNAALDH1A1TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020150263-A1 | SELECTIN OR GALECTIN ANTAGONISTS FOR TREATING CYTOKINE RELEASE SYNDROME AND CRS-INDUCED NEUROTOXICITY | MAGNANI JOHN L (US) | 2020-07-23 | — | — | WO | disclosed |