Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 4/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.34 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.32 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.32 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22248935 | 0.94 | ROCK2 (0.42) | ROCK2SIGMAR1MCHR1SPHK1 | |
| SCHEMBL22248674 | 0.87 | ROCK2 (0.47) | ROCK2SIGMAR1 | |
| SCHEMBL22254189 | 0.84 | ROCK2 (0.41) | ROCK2SIGMAR1L3MBTL3L3MBTL1MAPK14 | |
| SCHEMBL22248932 | 0.82 | ROCK2 (0.40) | ROCK2SIGMAR1MCHR1 | |
| SCHEMBL22248658 | 0.82 | ROCK2 (0.45) | ROCK2SIGMAR1L3MBTL3L3MBTL1 | |
| SCHEMBL22248949 | 0.79 | SPHK1 (0.47) | ROCK2L3MBTL3L3MBTL1MCHR1SPHK1 | |
| SCHEMBL22248957 | 0.78 | ROCK2 (0.41) | ROCK2SIGMAR1L3MBTL3L3MBTL1MCHR1 | |
| SCHEMBL22249159 | 0.78 | ROCK2 (0.46) | ROCK2 | |
| SCHEMBL22254225 | 0.77 | ROCK2 (0.44) | ROCK2L3MBTL3L3MBTL1MCHR1SPHK1 | |
| Hydrochloric Acid SCHEMBL30276621 | 0.76 | FAAH (0.35) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020150372-A1 | ANTIMICROBIAL COMPOUNDS AND METHODS | CURZA GLOBAL, LLC (US) | 2020-07-23 | — | — | WO | disclosed |