Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 4/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 13/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 12/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 9/20 | 0.37 |
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
| ▸ | NOS1 | P29475 | 1/20 | 0.36 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22248935 | 0.88 | ROCK2 (0.42) | ROCK2SIGMAR1OPRM1KCNH2NOS3 | |
| SCHEMBL22254573 | 0.83 | ROCK2 (0.49) | ROCK2KCNH2NOS3NOS1L3MBTL3 | |
| SCHEMBL22248446 | 0.82 | ROCK2 (0.39) | ROCK2SIGMAR1L3MBTL3L3MBTL1 | |
| SCHEMBL22248946 | 0.81 | ROCK2 (0.46) | ROCK2SIGMAR1OPRM1KCNH2NOS3 | |
| SCHEMBL22248674 | 0.79 | ROCK2 (0.47) | ROCK2SIGMAR1OPRM1 | |
| SCHEMBL22249174 | 0.78 | ROCK2 (0.43) | ROCK2SIGMAR1OPRM1KCNH2NOS3 | |
| Hydrochloric Acid SCHEMBL30276571 | 0.78 | OPRM1 (0.34) | ROCK2SIGMAR1OPRM1KCNH2HTR2A | |
| SCHEMBL22254568 | 0.77 | ROCK2 (0.47) | ROCK2SIGMAR1KCNH2NOS3NOS1 | |
| SCHEMBL22248433 | 0.77 | ROCK2 (0.42) | ROCK2SIGMAR1OPRM1KCNH2NOS3 | |
| SCHEMBL22249185 | 0.77 | ROCK2 (0.45) | ROCK2OPRM1KCNH2NOS3NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020150372-A1 | ANTIMICROBIAL COMPOUNDS AND METHODS | CURZA GLOBAL, LLC (US) | 2020-07-23 | — | — | WO | disclosed |