Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 5/20 | 0.34 |
| ▸ | MKNK2 | Q9HBH9 | 5/20 | 0.34 |
| ▸ | ABL1 | P00519 | 4/20 | 0.34 |
| ▸ | BCR | P11274 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | RET | P07949 | 5/20 | 0.33 |
| ▸ | CSF1R | P07333 | 2/20 | 0.33 |
| ▸ | YES1 | P07947 | 2/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.33 |
| ▸ | FLT1 | P17948 | 2/20 | 0.33 |
| ▸ | FLT4 | P35916 | 2/20 | 0.33 |
| ▸ | FLT3 | P36888 | 2/20 | 0.33 |
| ▸ | MELK | Q14680 | 2/20 | 0.33 |
| ▸ | NTRK2 | Q16620 | 2/20 | 0.33 |
| ▸ | DDR2 | Q16832 | 2/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | DDR1 | Q08345 | 4/20 | 0.33 |
| ▸ | BTK | Q06187 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 3/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30276597 | 0.90 | ATM (0.32) | FAAHDDR1JAK1 | |
| SCHEMBL22235345 | 0.90 | FAAH (0.35) | MKNK1MKNK2ABL1BCRCYP3A4 | |
| SCHEMBL22249259 | 0.87 | JAK1 (0.37) | ABL1FAAHROCK2JAK1 | |
| SCHEMBL22236164 | 0.87 | JAK1 (0.37) | ABL1FAAHROCK2JAK1 | |
| SCHEMBL22249136 | 0.87 | AOC3 (0.37) | MKNK1MKNK2ABL1BCRCYP3A4 | |
| SCHEMBL22249126 | 0.87 | AOC3 (0.37) | MKNK1MKNK2ABL1BCRCYP3A4 | |
| SCHEMBL30276514 | 0.82 | HRH3 (0.35) | CYP3A4FAAHROCK2JAK1 | |
| SCHEMBL22254966 | 0.82 | MKNK1 (0.40) | MKNK1MKNK2ABL1BCRCYP3A4 | |
| SCHEMBL30276540 | 0.81 | JAK1 (0.38) | CYP3A4ROCK2NTRK1JAK1 | |
| SCHEMBL22235950 | 0.80 | JAK1 (0.37) | ABL1FAAHROCK2JAK1PRKAA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230072397-A1 | Antimicrobial Compounds and Methods | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2023-03-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230072397-A1 | Antimicrobial Compounds and Methods | MPO, NISCH, RPN2 | MKNK1 1209/4885MKNK2 1971/4885ABL1 117/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.