Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 5/20 | 0.46 |
| ▸ | PTPN11 | Q06124 | 13/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22248957 | 0.89 | ROCK2 (0.41) | ROCK2PTPN11MCHR1 | |
| SCHEMBL22248651 | 0.87 | ROCK2 (0.46) | ROCK2PTPN11 | |
| SCHEMBL22249159 | 0.85 | ROCK2 (0.46) | ROCK2 | |
| SCHEMBL22248654 | 0.84 | ROCK2 (0.50) | ROCK2 | |
| SCHEMBL22248674 | 0.83 | ROCK2 (0.47) | ROCK2 | |
| SCHEMBL22248684 | 0.81 | ROCK2 (0.47) | ROCK2 | |
| SCHEMBL22248932 | 0.80 | ROCK2 (0.40) | ROCK2PTPN11MCHR1 | |
| SCHEMBL22254490 | 0.79 | ROCK2 (0.49) | ROCK2MCHR1 | |
| SCHEMBL22249164 | 0.77 | ROCK2 (0.47) | ROCK2MCHR1 | |
| SCHEMBL22249157 | 0.77 | ROCK2 (0.48) | ROCK2MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020150372-A1 | ANTIMICROBIAL COMPOUNDS AND METHODS | CURZA GLOBAL, LLC (US) | 2020-07-23 | — | — | WO | disclosed |