SCHEMBL2224969

SCHEMBL2224969

O=c1oc2cc(O)ccc2cc1-c1cccs1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 5/20 0.69
TMIGD3 P0DMS9 2/20 0.63
ADORA2A P29274 2/20 0.63
ADORA1 P30542 2/20 0.63
MIF P14174 8/20 0.61
NPC1 O15118 1/20 0.61
ESR2 Q92731 1/20 0.60
MAOA P21397 1/20 0.59
PTGS1 P23219 1/20 0.58
GPR35 Q9HC97 1/20 0.57
KDM4E B2RXH2 1/20 0.55
MEN1 O00255 1/20 0.55
ALDH1A1 P00352 1/20 0.55
GLA P06280 1/20 0.55
POLB P06746 1/20 0.55
GAA P10253 1/20 0.55
HPGD P15428 1/20 0.55
RAB9A P51151 1/20 0.55
KMT2A Q03164 1/20 0.55
NPSR1 Q6W5P4 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7585916 1.00 MAOB (0.69) MAOBTMIGD3ADORA2AADORA1MIF
SCHEMBL5940780 0.84 MIF (0.73) MAOBMIFNPC1ESR2PTGS1
SCHEMBL8116861 0.84 GPR35 (0.70) MAOBTMIGD3ADORA2AADORA1MIF
SCHEMBL24240003 0.83 MAOB (0.69) MAOBTMIGD3ADORA2AADORA1MIF
SCHEMBL19832052 0.83 MAOB (0.80) MAOBTMIGD3ADORA2AADORA1MIF
SCHEMBL30349901 0.83 MAOB (0.69) MAOBTMIGD3ADORA2AADORA1MIF
SCHEMBL23747968 0.83 MAOB (0.69) MAOBTMIGD3ADORA2AADORA1NPC1
SCHEMBL6931761 0.83 MAOB (0.69) MAOBTMIGD3ADORA2AADORA1MIF
SCHEMBL11910017 0.82 MAOB (0.52) MAOBMIFNPC1ESR2PTGS1
SCHEMBL21496231 0.82 MAOB (1.00) MAOBTMIGD3ADORA2AADORA1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2516666-B1 METHODS OF DETECTING MICROORGANISMS AND KITS THEREFORE 3M INNOVATIVE PROPERTIES CO (US) 2016-04-20 EP claimed
CN-102686739-B Methods of detecting microorganisms and kits therefore 3M INNOVATIVE PROPERTIES CO 2014-09-24 CN claimed
US-8802429-B2 System for detecting microorganisms 3M INNOVATIVE PROPERTIES COMPANY (US) 2014-08-12 US claimed
US-20130316443-A1 SYSTEM FOR DETECTING MICROORGANISMS 3M INNOVATIVE PROPERTIES COMPANY (US) 2013-11-28 US claimed
US-8518664-B2 Methods of determining the amount of microorganisms present in a test sample 3M INNOVATIVE PROPERTIES COMPANY (US) 2013-08-27 US claimed
EP-2516666-A1 METHODS OF DETECTING MICROORGANISMS AND KITS THEREFORE 3M Innovative Properties Company (US) 2012-10-31 EP claimed
US-20120252049-A1 METHODS OF DETECTING MICROORGANISMS AND KITS THEREFORE 3M INNOVATIVE PROPERTIES COMPANY 2012-10-04 US claimed
CN-102686739-A Methods of detecting microorganisms and kits therefore 3M INNOVATIVE PROPERTIES CO 2012-09-19 CN claimed
WO-2011087711-A1 METHODS OF DETECTING MICROORGANISMS AND KITS THEREFORE 3M INNOVATIVE PROPERTIES COMPANY (US) 2011-07-21 WO claimed
US-9896711-B2 Fluorogenic or fluorophoric compounds and uses thereof 3M INNOVATIVE PROPERTIES COMPANY (US) 2018-02-20 US disclosed
US-9896711-B2 Fluorogenic or fluorophoric compounds and uses thereof 3M INNOVATIVE PROPERTIES COMPANY (US) 2018-02-20 US disclosed
US-20160340709-A1 FLUOROGENIC OR FLUOROPHORIC COMPOUNDS AND USES THEREOF 3M INNOVATIVE PROPERTIES COMPANY (US) 2016-11-24 US disclosed
US-20160340709-A1 FLUOROGENIC OR FLUOROPHORIC COMPOUNDS AND USES THEREOF 3M INNOVATIVE PROPERTIES COMPANY (US) 2016-11-24 US disclosed
US-9434975-B2 Fluorogenic or fluorophoric compounds and uses thereof 3M INNOVATIVE PROPERTIES COMPANY (US) 2016-09-06 US disclosed
EP-1204671-B1 FLUOROGENIC COMPOUNDS AND USES THEREFOR 3M INNOVATIVE PROPERTIES CO (US) 2003-12-03 EP disclosed
US-6566508-B2 Compound for use in the accurate detection of food parasites 3M INNOVATIVE PROPERTIES COMPANY 2003-05-20 US disclosed
US-20020147317-A1 Fluorogenic compounds and uses therefor 3M INNOVATIVE PROPETIES COMPANY 2002-10-10 US disclosed
EP-1204671-A1 FLUOROGENIC COMPOUNDS AND USES THEREFOR 3M Innovative Properties Company (US) 2002-05-15 EP disclosed
US-6372895-B1 USEFUL IN ASSAYING FOR BIOLOGICAL ACTIVITY 3M INNOVATIVE PROPERTIES COMPANY 2002-04-16 US disclosed
WO-2001010881-A1 FLUOROGENIC COMPOUNDS AND USES THEREFOR 3M INNOVATIVE PROPERTIES COMPANY (US) 2001-02-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020147317-A1 Fluorogenic compounds and uses therefor NOTUM, WEE1, CPSF7 MAOB 3070/4885TMIGD3 1950/4885ADORA2A 4857/4885
US-20160340709-A1 FLUOROGENIC OR FLUOROPHORIC COMPOUNDS AND USES THEREOF FDPS, FOS, PFKFB1 MAOB 203/4885TMIGD3 4745/4885ADORA2A 3572/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.