Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.40 |
| ▸ | LCK | P06239 | 2/20 | 0.39 |
| ▸ | KIT | P10721 | 2/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22235128 | 0.89 | MET (0.42) | ALDH1A1KDM4EMAPTCA12CA1 | |
| SCHEMBL24297150 | 0.89 | KDM4E (0.40) | ALDH1A1KDM4EMAPTCA12CA1 | |
| SCHEMBL3665276 | 0.82 | AXL (0.49) | ALDH1A1KDM4ENPC1LCKKIT | |
| SCHEMBL17907416 | 0.82 | TSHR (0.48) | ALDH1A1KDM4EMAPTTSHRMEN1 | |
| SCHEMBL22234429 | 0.81 | MET (0.41) | ALDH1A1KDM4ELCKKITHPGD | |
| SCHEMBL22234532 | 0.77 | MET (0.43) | LCKKITAXLMETPLK4 | |
| SCHEMBL16366161 | 0.73 | LMNA (0.41) | ALDH1A1KDM4EMAPTTDP1LCK | |
| SCHEMBL22249523 | 0.72 | NPC1 (0.50) | ALDH1A1KDM4ECA12CA1CA2 | |
| SCHEMBL30030602 | 0.72 | MET (0.42) | ALDH1A1MAPTLCKKITTSHR | |
| SCHEMBL23749324 | 0.72 | MET (0.41) | ALDH1A1MAPTSMN1; SMN2LCKKIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020150307-A1 | PHOSPHONATE CONJUGATES AND USES THEREOF | THE TRANSLATIONAL GENOMICS RESEARCH INSTITUTE (US) | 2020-07-23 | — | — | WO | disclosed |