Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.45 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15506038 | 0.88 | GLA (0.43) | TSHRALDH1A1PDE4DKMT2ALMNA | |
| SCHEMBL3665276 | 0.87 | AXL (0.49) | ALDH1A1KDM4EPDE4DMEN1KMT2A | |
| SCHEMBL16386606 | 0.85 | KDM4E (0.51) | TSHRRECQLALDH1A1KDM4EPDE4D | |
| SCHEMBL22249751 | 0.82 | ALDH1A1 (0.41) | TSHRRECQLALDH1A1KDM4EPDE4D | |
| SCHEMBL16366161 | 0.80 | LMNA (0.41) | RECQLALDH1A1KDM4EPDE4DMEN1 | |
| SCHEMBL24297150 | 0.80 | KDM4E (0.40) | TSHRRECQLALDH1A1KDM4EPDE4D | |
| SCHEMBL22235128 | 0.80 | MET (0.42) | ALDH1A1KDM4EPDE4DMAPTTP53 | |
| SCHEMBL22234429 | 0.79 | MET (0.41) | ALDH1A1KDM4EPDE4DTP53 | |
| SCHEMBL11627353 | 0.77 | COMT (0.55) | TSHRRECQLALDH1A1KDM4EPDE4D | |
| SCHEMBL21383502 | 0.76 | MET (0.43) | ALDH1A1KDM4EPDE4DMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230172914-A1 | BIOMARKER-BASED THERAPEUTIC COMPOSITION | WELLMARKER BIO CO., LTD. (KR) | 2023-06-08 | — | — | US | disclosed |
| EP-3819300-A1 | BIOMARKER-BASED THERAPEUTIC COMPOSITION | Wellmarker Bio Co., Ltd. (KR) | 2021-05-12 | — | — | EP | disclosed |
| CN-112771053-A | Biomarker-based therapeutic compositions | 伟迈可生物有限公司 | 2021-05-07 | — | — | CN | disclosed |
| WO-2021045279-A1 | BIOMARKER-BASED THERAPEUTIC COMPOSITION | 웰마커바이오 주식회사 | 2021-03-11 | — | — | WO | disclosed |
| EP-3042905-B1 | PROTEIN KINASE INHIBITOR CONTAINING PYRROLOPYRIDAZINE DERIVATIVE | WELLMARKER BIO CO LTD (KR) | 2020-06-17 | — | — | EP | disclosed |
| US-9815840-B2 | Protein kinase inhibitor containing pyrrolopyridazine derivative | THE ASAN FOUNDATION (KR) | 2017-11-14 | — | — | US | disclosed |
| US-20160207931-A1 | PROTEIN KINASE INHIBITOR CONTAINING PYRROLOPYRIDAZINE DERIVATIVE | CJ HEALTHCARE CORPORATION (KR) | 2016-07-21 | — | — | US | disclosed |
| EP-3042905-A1 | PROTEIN KINASE INHIBITOR CONTAINING PYRROLOPYRIDAZINE DERIVATIVE | CJ Healthcare Corporation (KR) | 2016-07-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230172914-A1 | BIOMARKER-BASED THERAPEUTIC COMPOSITION | KRAS, RET, NRAS | TSHR 1115/4885RECQL 3281/4885ALDH1A1 3257/4885 |
| US-20160207931-A1 | PROTEIN KINASE INHIBITOR CONTAINING PYRROLOPYRIDAZINE DERIVATIVE | MAPKAPK5, MAP3K5, PRKCA | TSHR 3922/4885RECQL 4070/4885ALDH1A1 2605/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.