Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | CTSK | P43235 | 9/20 | 0.47 |
| ▸ | CTSS | P25774 | 5/20 | 0.43 |
| ▸ | CA2 | P00918 | 3/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 2/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1763873 | 1.00 | CYP1A2 (0.49) | CYP1A2CYP2C9CYP2C19HTTCTSK | |
| SCHEMBL1317487 | 1.00 | CYP1A2 (0.49) | CYP1A2CYP2C9CYP2C19HTTCTSK | |
| SCHEMBL2390166 | 0.94 | CYP1A2 (0.49) | CYP1A2CYP2C9CYP2C19HTTCTSK | |
| SCHEMBL15418649 | 0.94 | CYP1A2 (0.49) | CYP1A2CYP2C9CYP2C19HTTCTSK | |
| SCHEMBL13076509 | 0.94 | CYP1A2 (0.49) | CYP1A2CYP2C9CYP2C19HTTCTSK | |
| SCHEMBL8056542 | 0.91 | CTSK (0.51) | CYP1A2CYP2C9CYP2C19HTTCTSK | |
| SCHEMBL13040188 | 0.91 | CTSK (0.51) | CYP1A2CYP2C9CYP2C19HTTCTSK | |
| SCHEMBL27847191 | 0.91 | CTSK (0.51) | CYP1A2CYP2C9CYP2C19HTTCTSK | |
| SCHEMBL11175129 | 0.90 | CYP1A2 (0.42) | CYP1A2CYP2C9CYP2C19HTTCTSK | |
| SCHEMBL19422705 | 0.89 | CYP1A2 (0.63) | CYP1A2CYP2C9CYP2C19HTTCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 122 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116332801-B | Preparation method of N-tert-butoxycarbonyl-L-glutamic acid dimethyl ester derivative | 阜阳欣奕华制药科技有限公司 | 2025-02-18 | — | — | CN | claimed |
| CN-115073347-B | Preparation method of lactam ring medical intermediate | 浙江江北药业有限公司 | 2024-07-30 | — | — | CN | claimed |
| CN-114605301-B | Method for preparing Pa Luo Weide intermediate | 江苏恒沛药物科技有限公司 | 2024-06-04 | — | — | CN | claimed |
| CN-114163347-B | Synthesis method of N-acyl glutamate | 镇江中智化学科技有限公司 | 2024-03-26 | — | — | CN | claimed |
| CN-116396191-A | Preparation method of N-tert-butoxycarbonyl-L-glutamic acid dimethyl ester derivative | 阜阳欣奕华制药科技有限公司 | 2023-07-07 | — | — | CN | claimed |
| CN-116332801-A | Preparation method of N-tert-butoxycarbonyl-L-glutamic acid dimethyl ester derivative | 阜阳欣奕华制药科技有限公司 | 2023-06-27 | — | — | CN | claimed |
| CN-115947670-A | Synthesis process of N-tert-butyloxycarbonyl-L-glutamic acid dimethyl ester | 常州吉恩药业有限公司 | 2023-04-11 | — | — | CN | claimed |
| CN-218741950-U | Reaction kettle for synthesizing N-tert-butyloxycarbonyl-L-glutamic acid dimethyl ester | 镇江中智化学科技有限公司 | 2023-03-28 | — | — | CN | claimed |
| CN-115073347-A | Preparation method of lactam ring pharmaceutical intermediate | 浙江江北药业有限公司 | 2022-09-20 | — | — | CN | claimed |
| CN-114605301-A | Method for preparing intermediate of palovir | 江苏恒沛药物科技有限公司 | 2022-06-10 | — | — | CN | claimed |
| CN-114163347-A | Synthesis method of N-acyl glutamate | 镇江中智化学科技有限公司 | 2022-03-11 | — | — | CN | claimed |
| US-12636275-B2 | Pharmaceutical use of ketoamide-based compound | SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) | 2026-05-26 | — | — | US | disclosed |
| CN-116332801-B | Preparation method of N-tert-butoxycarbonyl-L-glutamic acid dimethyl ester derivative | 阜阳欣奕华制药科技有限公司 | 2025-02-18 | — | — | CN | disclosed |
| CN-116332801-B | Preparation method of N-tert-butoxycarbonyl-L-glutamic acid dimethyl ester derivative | 阜阳欣奕华制药科技有限公司 | 2025-02-18 | — | — | CN | disclosed |
| CN-116332801-B | Preparation method of N-tert-butoxycarbonyl-L-glutamic acid dimethyl ester derivative | 阜阳欣奕华制药科技有限公司 | 2025-02-18 | — | — | CN | disclosed |
| EP-1532137-A2 | ANTIMICROBIAL AZA-BICYCLIC DERIVATES, THEIR COMPOSITIONS AND USES | THE PROCTER & GAMBLE COMPANY (US) | 2005-05-25 | — | — | EP | disclosed |
| US-20040038975-A1 | Antimicrobial quinolones, their compositions and uses | THE PROCTER & GAMBLE COMPANY | 2004-02-26 | — | — | US | disclosed |
| WO-2004014893-A2 | ANTIMICROBIAL AZA-BICYCLIC DERIVATES, THEIR COMPOSITIONS AND USES | THE PROCTER & GAMBLE COMPANY (US) | 2004-02-19 | — | — | WO | disclosed |
| US-6458948-B1 | MIXING A QUATERNARY AMMONIUM SALT HAVING A PARTICULAR TRIAZINE RING IN THE MOLECULES THEREOF, A CARBOXYLIC ACID COMPOUND AND A COMPOUND HAVING A NUCLEOPHILIC FUNCTIONAL GROUP, TO CONDENSE THE CARBOXYLIC ACID WITH THE COMPOUND HAVING THE NUCLEOPHILIC | TOKUYAMA CORPORATION (JP) | 2002-10-01 | — | — | US | disclosed |
| US-4452897-A | ENZYME HYDROLYSIS OF AMINOGLUTARIC ACID ALKYL ESTERS | TAKARA SHUZO CO., LTD. (JP) | 1984-06-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040038975-A1 | Antimicrobial quinolones, their compositions and uses | QARS1, NQO2, Q6ZSR9 | CYP1A2 184/4885CYP2C9 252/4885CYP2C19 127/4885 |
| US-12636275-B2 | Pharmaceutical use of ketoamide-based compound | CTSV, CTSL, CTSS | CYP1A2 740/4885CYP2C9 264/4885CYP2C19 197/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.