SCHEMBL22255607

SCHEMBL22255607

c1ccc(-c2ccccc2-c2ccc(N(c3ccc(-c4cc5ccccc5cc4-c4ccccc4)cc3)c3cccc4sc5ccccc5c34)cc2)cc1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
F9 P00740 1/20 0.35
PTGS2 P35354 1/20 0.33
S1PR5 Q9H228 8/20 0.33
S1PR4 O95977 6/20 0.33
ALOX5 P09917 1/20 0.33
SLC9A1 P19634 1/20 0.32
CRHR1 P34998 1/20 0.32
ALDH1A1 P00352 3/20 0.31
HPGD P15428 3/20 0.31
TSHR P16473 2/20 0.31
MAPK1 P28482 2/20 0.31
CASP1 P29466 2/20 0.31
HIF1A Q16665 2/20 0.31
HSD17B10 Q99714 2/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
GPR84 Q9NQS5 1/20 0.31
TP53 P04637 1/20 0.31
CASP7 P55210 1/20 0.31
LIMK1 P53667 1/20 0.31
GPR3 P46089 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22255610 0.96 F9 (0.33) F9PTGS2S1PR5S1PR4ALOX5
SCHEMBL21203362 0.96 PTGS2 (0.34) F9PTGS2S1PR5S1PR4ALOX5
SCHEMBL22255685 0.96 PTGS2 (0.34) F9PTGS2S1PR5S1PR4ALOX5
SCHEMBL22452167 0.96 PTGS2 (0.34) F9PTGS2S1PR5S1PR4ALOX5
SCHEMBL22255682 0.95 F9 (0.39) F9S1PR5S1PR4SLC9A1
SCHEMBL22255608 0.95 ALDH1A1 (0.36) F9PTGS2S1PR5S1PR4ALOX5
SCHEMBL23258051 0.93 ALDH1A1 (0.35) F9ALOX5SLC9A1CRHR1ALDH1A1
SCHEMBL22255684 0.93 CYP11B1 (0.35) F9PTGS2ALDH1A1HPGDTSHR
SCHEMBL22255686 0.93 F9 (0.34) F9PTGS2S1PR5S1PR4ALOX5
SCHEMBL24370073 0.92 F9 (0.37) F9ALOX5SLC9A1CRHR1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200235297-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND MONOAMINE COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2020-07-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200235297-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND MONOAMINE COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE SLC18A2, SLC18A1, MAOA F9 2570/4885PTGS2 3330/4885S1PR5 3891/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.