Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 8/20 | 0.63 |
| ▸ | CTSK | P43235 | 6/20 | 0.63 |
| ▸ | CTSB | P07858 | 5/20 | 0.63 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.55 |
| ▸ | MMP9 | P14780 | 1/20 | 0.54 |
| ▸ | MMP8 | P22894 | 1/20 | 0.54 |
| ▸ | JAK3 | P52333 | 1/20 | 0.52 |
| ▸ | BTK | Q06187 | 1/20 | 0.52 |
| ▸ | ACE | P12821 | 2/20 | 0.47 |
| ▸ | TACR1 | P25103 | 1/20 | 0.46 |
| ▸ | CTSL | P07711 | 3/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | MME | P08473 | 1/20 | 0.45 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.44 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.43 |
| ▸ | PPIA | P62937 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5993911 | 1.00 | CTSS (0.63) | CTSSCTSKCTSBPTPN1MMP9 | |
| SCHEMBL29436793 | 1.00 | CTSS (0.63) | CTSSCTSKCTSBPTPN1MMP9 | |
| SCHEMBL13680202 | 0.90 | MMP9 (0.59) | CTSSCTSKCTSBPTPN1MMP9 | |
| SCHEMBL1204211 | 0.86 | JAK3 (0.61) | CTSSCTSKCTSBJAK3BTK | |
| SCHEMBL6557659 | 0.86 | JAK3 (0.61) | CTSSCTSKCTSBJAK3BTK | |
| SCHEMBL9929886 | 0.85 | CTSS (0.62) | CTSSCTSKCTSBPTPN1JAK3 | |
| SCHEMBL8185213 | 0.85 | CTSS (0.62) | CTSSCTSKCTSBPTPN1JAK3 | |
| SCHEMBL5630007 | 0.85 | CTSS (0.69) | CTSSCTSKCTSBPTPN1MMP9 | |
| SCHEMBL31584535 | 0.85 | CTSS (0.69) | CTSSCTSKCTSBPTPN1MMP9 | |
| SCHEMBL2348036 | 0.85 | MMP9 (0.59) | CTSSCTSKCTSBPTPN1MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3911645-B1 | 5-MEMBERED HETEROARYL COMPOUNDS CONTAINING A HYDROXAMATE MOIETY AND THEIR USE | UNIV LILLE (FR) | 2022-12-07 | — | — | EP | disclosed |
| WO-2020148403-A1 | 5-MEMBERED HETEROARYL COMPOUNDS CONTAINING A HYDROXAMATE MOIETY AND THEIR USE | UNIVERSITE DE LILLE (FR) | 2020-07-23 | — | — | WO | disclosed |