SCHEMBL22256236

SCHEMBL22256236

Brc1ccc2ccc3c(-c4cccc(-c5c6ccccc6cc6ccccc56)c4)ccc4ccc1c2c43

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 5/20 0.45
ERBB2 P04626 1/20 0.45
FYN P06241 1/20 0.45
MAOA P21397 1/20 0.45
ACHE P22303 1/20 0.45
AHR P35869 1/20 0.45
CES1 P23141 1/20 0.40
ALOX5 P09917 2/20 0.39
ALDH1A1 P00352 3/20 0.37
HPGD P15428 2/20 0.37
HSD17B10 Q99714 2/20 0.37
THRB P10828 1/20 0.37
NQO2 P16083 2/20 0.35
DNMT1 P26358 1/20 0.33
CYP3A4 P08684 2/20 0.33
CYP2D6 P10635 2/20 0.33
CYP2C9 P11712 2/20 0.33
HSD17B1 P14061 2/20 0.33
CYP2B6 P20813 2/20 0.33
CYP2C19 P33261 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22256150 0.85 CYP1A2 (0.49) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL30647526 0.85 CYP1A2 (0.49) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL16632947 0.84 CYP1A2 (0.41) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL22256166 0.83 HSD17B1 (0.42) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL22256169 0.79 CRHBP (0.39) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL29950077 0.79 GSTP1 (0.46) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL2789682 0.79 GSTP1 (0.46) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL2293036 0.78 ALDH1A1 (0.43) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL2292638 0.78 ALDH1A1 (0.43) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL22256004 0.78 CYP1A2 (0.41) CYP1A2ERBB2FYNMAOAACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200235320-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME LUMINESCENCE TECHNOLOGY CORPORATION (TW) 2020-07-23 US disclosed