SCHEMBL22257519

SCHEMBL22257519

NC(=O)CCSCCC[Si](O)(O)O

nearest known ligand 0.37

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.37
LMNA P02545 1/20 0.37
HSD17B10 Q99714 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
BHMT Q93088 2/20 0.35
TSHR P16473 1/20 0.34
ALOX15 P16050 1/20 0.31
BLM P54132 1/20 0.31
PMP22 Q01453 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL788769 0.81 KMT2A (0.53) KMT2ALMNAHSD17B10TDP1BHMT
SCHEMBL3068716 0.78 TSHR (0.44) KMT2ALMNAHSD17B10TDP1BHMT
SCHEMBL11938132 0.78 KMT2A (0.50) KMT2ALMNAHSD17B10TDP1BHMT
SCHEMBL4858666 0.77 TDP1 (0.40) KMT2ALMNAHSD17B10TDP1BHMT
SCHEMBL11862251 0.76 FAAH (0.45) KMT2ALMNAHSD17B10TDP1TSHR
SCHEMBL19838190 0.74 BHMT (0.61) KMT2ALMNAHSD17B10TDP1BHMT
SCHEMBL10339731 0.74 CES2 (0.50) KMT2AHSD17B10BLM
SCHEMBL14157749 0.72 CES2 (0.53) KMT2AHSD17B10TSHRBLM
SCHEMBL5069976 0.72 CES2 (0.53) KMT2AHSD17B10TSHRBLM
SCHEMBL9313907 0.72 CES2 (0.53) KMT2AHSD17B10TSHRBLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230322989-A1 BONDING DISSIMILAR POLYMER NETWORKS IN VARIOUS MANUFACTURING PROCESSES NATIONAL SCIENCE FOUNDATION 2023-10-12 US disclosed
US-11702495-B2 Bonding dissimilar polymer networks in various manufacturing processes PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2023-07-18 US disclosed
US-11702495-B2 Bonding dissimilar polymer networks in various manufacturing processes PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2023-07-18 US disclosed
US-20200231728-A1 BONDING DISSIMILAR POLYMER NETWORKS IN VARIOUS MANUFACTURING PROCESSES PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2020-07-23 US disclosed