SCHEMBL788769

SCHEMBL788769

NC(=O)CCSCCC(N)=O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.53
LMNA P02545 2/20 0.53
HSD17B10 Q99714 2/20 0.53
TDP1 Q9NUW8 2/20 0.53
ALOX15 P16050 2/20 0.42
BLM P54132 2/20 0.42
PMP22 Q01453 2/20 0.42
ALDH1A1 P00352 3/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
HPGD P15428 2/20 0.37
CYP1A2 P05177 3/20 0.37
KDM4E B2RXH2 1/20 0.37
GMNN O75496 1/20 0.37
USP2 O75604 1/20 0.37
TP53 P04637 1/20 0.37
GLA P06280 1/20 0.37
POLB P06746 1/20 0.37
CYP3A4 P08684 1/20 0.37
CYP2C9 P11712 1/20 0.37
CYP2C19 P33261 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11938132 0.97 KMT2A (0.50) KMT2ALMNAHSD17B10TDP1ALOX15
SCHEMBL1106831 0.89
SCHEMBL10024581 0.89
SCHEMBL1106829 0.89 LMNA (0.74) KMT2ALMNAHSD17B10TDP1ALOX15
SCHEMBL15147841 0.88 KMT2A (0.41) KMT2ALMNAHSD17B10TDP1ALOX15
SCHEMBL24169230 0.87
SCHEMBL9162190 0.87
SCHEMBL4858666 0.84 TDP1 (0.40) KMT2ALMNAHSD17B10TDP1ALOX15
SCHEMBL3068716 0.84 TSHR (0.44) KMT2ALMNAHSD17B10TDP1ALOX15
SCHEMBL11713291 0.83

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 76 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108882704-B Molecules having pesticidal utility, and intermediates, compositions and methods related to these molecules 美国陶氏益农公司 2021-09-10 CN claimed
US-4306048-A Method for preparing acrylamide polymers NITTO CHEMICAL INDUSTRY CO., LTD. (JP) 1981-12-15 US claimed
EP-4400492-A1 ACRIDINE COMPOUND OSAKA UNIVERSITY (JP) 2024-07-17 EP disclosed
US-20240208999-A1 HETEROCYCLIC COMPOUND OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2024-06-27 US disclosed
EP-4370507-A1 HYDROGENATED QUINOXALINES Otsuka Pharmaceutical Co., Ltd. (JP) 2024-05-22 EP disclosed
CN-117940408-A Acridine compounds 国立大学法人大阪大学 2024-04-26 CN disclosed
EP-4347597-A1 PYRAZOLO[1,5-A]PYRIMIDINE COMPOUND FOR THE TREATMENT OF DERMAL DISORDERS Otsuka Pharmaceutical Co., Ltd. (JP) 2024-04-10 EP disclosed
US-20240109842-A1 ACRYLAMIDE COMPOUNDS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2024-04-04 US disclosed
US-11932657-B2 Heterocyclic compound OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2024-03-19 US disclosed
CN-117616013-A Hydrogenated quinoxalines 大塚制药株式会社 2024-02-27 CN disclosed
CN-117377674-A Pyrazolo [1,5-a ] pyrimidine compounds for the treatment of dermatological disorders 大塚制药株式会社 2024-01-09 CN disclosed
WO-2003060192-A1 NON-TOXIC CORROSION-PROTECTION RINSES AND SEALS BASED ON COBALT UNIVERSITY OF DAYTON (US) 2003-07-24 WO disclosed
EP-0407123-B1 Films for packaged articles eliminating air entrapment DU PONT (US) 1996-10-09 EP disclosed
EP-0475160-B1 Preparation for drug application in minute droplet form IDEA AG (DE) 1996-02-14 EP disclosed
US-5162154-A Packaging smooth-surfaced article with transparent film having surface of a polymer which in film form exhibits specular gloss of at least 20, measured at angle of 20 degrees, and synthetic amorphous silica of 0.5-50 micrometer particle size E. I. DU PONT DE NEMOURS AND COMPANY (US) 1992-11-10 US disclosed
EP-0407123-A2 Films for packaged articles eliminating air entrapment E.I. DU PONT DE NEMOURS AND COMPANY (US) 1991-01-09 EP disclosed
US-4569766-A MALEIMIDES THE STANDARD OIL COMPANY (US) 1986-02-11 US disclosed
US-4306048-A Method for preparing acrylamide polymers NITTO CHEMICAL INDUSTRY CO., LTD. (JP) 1981-12-15 US disclosed
US-4243762-A Alkanolamine processing aid for ethylene-vinyl ester interpolymer particles present in aqueous dispersions thereof NATIONAL DISTILLERS AND CHEMICAL CORP. (US) 1981-01-06 US disclosed
US-4105763-A 1-Methyl-2-(phenyl-oxymethyl)-5-nitro-imidazoles HOECHST AKTIENGESELLSCHAFT (DE) 1978-08-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240109842-A1 ACRYLAMIDE COMPOUNDS HPGDS, MYADM, ACR KMT2A 2079/4885LMNA 1924/4885HSD17B10 2917/4885
US-11932657-B2 Heterocyclic compound AHR, PDGFRA, PDGFRB KMT2A 1736/4885LMNA 3284/4885HSD17B10 691/4885
US-20240208999-A1 HETEROCYCLIC COMPOUND AHR, PDGFRA, PDGFRB KMT2A 1736/4885LMNA 3284/4885HSD17B10 691/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.