Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29003644 | 0.82 | KMT2A (0.57) | ALDH1A1KMT2APOLBGAAMAPT | |
| SCHEMBL6538715 | 0.78 | ALDH1A1 (0.56) | ALDH1A1TSHRTP53SRD5A2KMT2A | |
| SCHEMBL29003606 | 0.77 | LOXL2 (0.58) | ALDH1A1TSHRKMT2AKDM4EMEN1 | |
| SCHEMBL211305 | 0.77 | ALDH1A1 (0.54) | ALDH1A1TSHRTP53SRD5A2KMT2A | |
| SCHEMBL4141280 | 0.77 | ALDH1A1 (0.54) | ALDH1A1TSHRTP53SRD5A2KMT2A | |
| SCHEMBL3633156 | 0.75 | FFAR1 (0.44) | ALDH1A1TSHRTP53THRBTDP1 | |
| Terephthalic Acid SCHEMBL6664013 | 0.74 | TSHR (0.92) | ALDH1A1TSHRTP53SRD5A2SMN1; SMN2 | |
| SCHEMBL70166 | 0.72 | TSHR (0.67) | ALDH1A1TSHRTP53SRD5A2KMT2A | |
| Terephthalic Acid SCHEMBL4612225 | 0.72 | TSHR (0.67) | ALDH1A1TSHRTP53SRD5A2KMT2A | |
| SCHEMBL68390 | 0.72 | SRD5A2 (0.69) | ALDH1A1TSHRTP53SRD5A2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2521727-A1 | NOVEL BENZOIC PYRROLOPYRIDINE DERIVATIVES | Laboratoires Fournier S.A. (FR) | 2012-11-14 | — | — | EP | disclosed |
| WO-2011083278-A1 | NOVEL BENZOIC PYRROLOPYRIDINE DERIVATIVES | LABORATOIRES FOURNIER SA (FR) | 2011-07-14 | — | — | WO | disclosed |