Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | ACACB | O00763 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2225820 | 0.82 | ALDH1A1 (0.52) | KMT2AHSD17B10MAPTL3MBTL1HPGD | |
| SCHEMBL29003606 | 0.79 | LOXL2 (0.58) | KMT2ALMNAHSD17B10MAPTHPGD | |
| SCHEMBL27263454 | 0.79 | KMT2A (0.68) | KMT2ALMNAPYCR1HSD17B10ACACB | |
| SCHEMBL9142779 | 0.78 | KMT2A (0.59) | KMT2ALMNAPYCR1HSD17B10ACACB | |
| SCHEMBL6859304 | 0.73 | KMT2A (1.00) | KMT2ALMNAPYCR1HSD17B10MAOB | |
| SCHEMBL9818052 | 0.73 | KMT2A (0.73) | KMT2ALMNAPYCR1HSD17B10MAOB | |
| SCHEMBL50646 | 0.72 | MAPT (0.68) | KMT2ALMNAMAPTL3MBTL1HPGD | |
| SCHEMBL8787884 | 0.72 | CYP4F2 (0.56) | KMT2ALMNAMAPTL3MBTL1HPGD | |
| SCHEMBL7692352 | 0.72 | KMT2A (0.70) | KMT2ALMNAPYCR1HSD17B10MAOB | |
| SCHEMBL334751 | 0.72 | KMT2A (0.70) | KMT2ALMNAPYCR1HSD17B10MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115947668-A | Preparation method of polysubstituted indene derivative | 广东工业大学 | 2023-04-11 | — | — | CN | disclosed |