SCHEMBL22258707

SCHEMBL22258707

Clc1nc(Cl)c2ccc3sc4c5ccccc5ccc4c3c2n1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A1 P04798 5/20 0.38
CYP1B1 Q16678 5/20 0.38
CYP1A2 P05177 4/20 0.38
MAPT P10636 2/20 0.37
CYP3A4 P08684 2/20 0.37
MAPK1 P28482 2/20 0.37
LMNA P02545 1/20 0.37
APEX1 P27695 1/20 0.37
PMP22 Q01453 1/20 0.37
L3MBTL1 Q9Y468 2/20 0.35
RAB9A P51151 2/20 0.33
NPC1 O15118 1/20 0.33
HPRT1 P00492 1/20 0.33
CYP2A6 P11509 3/20 0.33
TSHR P16473 2/20 0.31
HSD17B10 Q99714 2/20 0.31
ALDH1A1 P00352 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
PRNP P04156 1/20 0.31
EGLN1 Q9GZT9 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22258682 0.88 MAPT (0.37) CYP1A1CYP1B1CYP1A2MAPTCYP3A4
SCHEMBL18853714 0.87 MAPT (0.35) CYP1A1CYP1B1CYP1A2MAPTCYP3A4
SCHEMBL19758769 0.85 GPR3 (0.39) CYP1A2MAPTCYP3A4RAB9ANPC1
SCHEMBL22258673 0.83 CYP1A1 (0.41) CYP1A1CYP1B1CYP1A2MAPTCYP3A4
SCHEMBL22258754 0.82 CYP1A1 (0.40) CYP1A1CYP1B1CYP1A2MAPTCYP3A4
SCHEMBL22258321 0.81
SCHEMBL22259099 0.80 CYP1A1 (0.41) CYP1A1CYP1B1CYP1A2MAPTLMNA
SCHEMBL18853655 0.80 CYP1B1 (0.40) CYP1A1CYP1B1CYP1A2MAPTCYP3A4
SCHEMBL30184670 0.79 MAPT (0.51) CYP1A1CYP1B1CYP1A2MAPTCYP3A4
SCHEMBL18688165 0.79 MAPT (0.51) CYP1A1CYP1B1CYP1A2MAPTCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11211568-B2 Compound for organic electroluminescence device using the same LUMINESCENCE TECHNOLOGY CORP. (TW) 2021-12-28 US disclosed
US-20200235311-A1 COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME LUMINESCENCE TECHNOLOGY CORPORATION (TW) 2020-07-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11211568-B2 Compound for organic electroluminescence device using the same OR10J3, PIEZO1, ICMT CYP1A1 1338/4885CYP1B1 1612/4885CYP1A2 1343/4885
US-20200235311-A1 COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME OR10J3, PIEZO1, ICMT CYP1A1 1338/4885CYP1B1 1612/4885CYP1A2 1343/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.