SCHEMBL22258754

SCHEMBL22258754

Clc1nc(-c2cccc3ccccc23)c2ccc3sc4c5ccccc5ccc4c3c2n1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A1 P04798 5/20 0.40
CYP1B1 Q16678 5/20 0.40
CYP1A2 P05177 4/20 0.37
TGFBR1 P36897 1/20 0.32
MAPT P10636 3/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
RIPK2 O43353 1/20 0.31
PRKD3 O94806 1/20 0.31
ABL1 P00519 1/20 0.31
FYN P06241 1/20 0.31
SRC P12931 1/20 0.31
CDK2 P24941 1/20 0.31
CSK P41240 1/20 0.31
MAPK8 P45983 1/20 0.31
CSNK1D P48730 1/20 0.31
PRKCE Q02156 1/20 0.31
PRKD1 Q15139 1/20 0.31
PRKD2 Q9BZL6 1/20 0.31
CAMK2A Q9UQM7 1/20 0.31
BCHE P06276 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22258720 0.90 CYP1A1 (0.34) CYP1A1CYP1B1CYP1A2TGFBR1MAPT
SCHEMBL22258681 0.86 CYP1A1 (0.33) CYP1A1CYP1B1CYP1A2TGFBR1MAPT
SCHEMBL22258673 0.86 CYP1A1 (0.41) CYP1A1CYP1B1CYP1A2MAPTL3MBTL1
SCHEMBL22259099 0.82 CYP1A1 (0.41) CYP1A1CYP1B1CYP1A2MAPTL3MBTL1
SCHEMBL22258707 0.82 CYP1A1 (0.38) CYP1A1CYP1B1CYP1A2MAPTL3MBTL1
SCHEMBL18132493 0.82 MAPT (0.45) CYP1A2TGFBR1MAPTL3MBTL1BCHE
SCHEMBL17305860 0.79 ALOX5 (0.37) CYP1A1CYP1B1MAPT
SCHEMBL22258639 0.79 CYP1A1 (0.41) CYP1A1CYP1B1CYP1A2MAPTL3MBTL1
SCHEMBL17297448 0.79 LIMK1 (0.37) CYP1A2TGFBR1MAPTBCHEALDH1A1
SCHEMBL22258724 0.78 CYP1A1 (0.40) CYP1A1CYP1B1CYP1A2MAPTL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11211568-B2 Compound for organic electroluminescence device using the same LUMINESCENCE TECHNOLOGY CORP. (TW) 2021-12-28 US disclosed
US-20200235311-A1 COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME LUMINESCENCE TECHNOLOGY CORPORATION (TW) 2020-07-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11211568-B2 Compound for organic electroluminescence device using the same OR10J3, PIEZO1, ICMT CYP1A1 1338/4885CYP1B1 1612/4885CYP1A2 1343/4885
US-20200235311-A1 COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME OR10J3, PIEZO1, ICMT CYP1A1 1338/4885CYP1B1 1612/4885CYP1A2 1343/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.