Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.38 |
| ▸ | PIP5K1C | O60331 | 4/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.37 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.37 |
| ▸ | PIP5K1B | O14986 | 1/20 | 0.37 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | PIP5K1A | Q99755 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13314749 | 0.76 | SMN1; SMN2 (0.50) | RAB9ASMN1; SMN2KDM4EHSD17B10ADORA2A | |
| SCHEMBL3579872 | 0.73 | ALDH1A1 (0.47) | RAB9ASMN1; SMN2KDM4EHSD17B10NPC1 | |
| SCHEMBL22258960 | 0.72 | CYP3A4 (0.41) | KDM4ELMNAALDH1A1L3MBTL1MAPT | |
| SCHEMBL3588865 | 0.71 | KMT2A (0.45) | RAB9ASMN1; SMN2KDM4ENPC1ALDH1A1 | |
| SCHEMBL22258666 | 0.70 | SCN9A (0.35) | RAB9AKDM4EHSD17B10ADORA2AADORA1 | |
| SCHEMBL13314757 | 0.69 | KMT2A (0.54) | RAB9ASMN1; SMN2KDM4ENPC1ALDH1A1 | |
| SCHEMBL13314770 | 0.69 | NPC1 (0.54) | RAB9ASMN1; SMN2KDM4EHSD17B10ADORA2A | |
| SCHEMBL23719268 | 0.68 | ADORA3 (0.51) | RAB9ASMN1; SMN2ADORA2AADORA2BADORA1 | |
| SCHEMBL13314750 | 0.67 | NPC1 (0.49) | RAB9ANPC1ALDH1A1MAPT | |
| SCHEMBL415065 | 0.67 | TGFBR1 (0.70) | ADORA2AADORA2BADORA1PIP5K1CPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020150545-A1 | PYRAZOLE DERIVATIVES AS MODULATORS OF THE WNT/B-CATENIN SIGNALING PATHWAY | SAMUMED, LLC (US) | 2020-07-23 | — | — | WO | disclosed |