Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | PLA2G2A | P14555 | 5/20 | 0.39 |
| ▸ | PLA2G4A | P47712 | 5/20 | 0.39 |
| ▸ | AHR | P35869 | 2/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | TNKS | O95271 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GABRP | O00591 | 1/20 | 0.35 |
| ▸ | GABRD | O14764 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25608187 | 0.96 | NPC1 (0.40) | NPC1HPGDMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL18212070 | 0.94 | NPC1 (0.41) | NPC1HPGDMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL18212124 | 0.93 | PLA2G2A (0.42) | NPC1HPGDMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL24472294 | 0.92 | AHR (0.41) | NPC1HPGDMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL24472253 | 0.92 | AHR (0.41) | NPC1HPGDMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL24472512 | 0.92 | AHR (0.41) | NPC1HPGDMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL25580194 | 0.91 | KDM4E (0.34) | NPC1HPGDMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL25580274 | 0.91 | KDM4E (0.34) | NPC1HPGDMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL24472510 | 0.90 | AHR (0.40) | NPC1HPGDMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL19598814 | 0.90 | PLA2G2A (0.44) | NPC1HPGDMAPTRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200231534-A1 | ARYLDIAMINE COMPOUND AND ORGANIC ELECTROLUMINESCENT ELEMENT | HODOGAYA CHEMICAL CO., LTD. (JP) | 2020-07-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200231534-A1 | ARYLDIAMINE COMPOUND AND ORGANIC ELECTROLUMINESCENT ELEMENT | FTO, SLC19A1, ALKBH1 | NPC1 1052/4885HPGD 3574/4885MAPT 1146/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.