SCHEMBL222605

SCHEMBL222605

C[Si](C)(C)C(C(N)=O)[Si](C)(C)C

nearest known ligand 0.35

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.35
ALOX15 P16050 1/20 0.35
BLM P54132 1/20 0.35
PMP22 Q01453 1/20 0.35
ALDH1A1 P00352 1/20 0.31
OR51E2 Q9H255 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3586576 0.97 LMNA (0.33) LMNAALOX15BLMPMP22
SCHEMBL11142184 0.83
SCHEMBL3645450 0.73 LMNA (0.35) LMNAALOX15BLMPMP22ALDH1A1
SCHEMBL5435336 0.73 CA1 (0.34) LMNAALOX15BLMPMP22
SCHEMBL8312889 0.73 LMNA (0.30) LMNAALOX15BLMPMP22
SCHEMBL5477218 0.71
SCHEMBL4746690 0.71 TDP1 (0.41) TDP1
SCHEMBL10583658 0.71
SCHEMBL7098668 0.71
SCHEMBL30723428 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4943 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4735459-A1 METHODS AND INTERMEDIATES FOR PREPARING ANTIVIRAL PRODRUGS GILEAD SCIENCES, INC. (US) 2026-05-06 EP claimed
WO-2025032082-A1 PROCESS FOR THE PREPARATION OF 3-SUBSTITUTED 5-AMINO-6H-THIAZOLO[4,5-D]PYRIMIDINE-2,7-DIONE COMPOUNDS F. HOFFMANN-LA ROCHE AG (CH) 2025-02-13 WO claimed
WO-2025006582-A1 METHODS AND INTERMEDIATES FOR PREPARING ANTIVIRAL PRODRUGS GILEAD SCIENCES, INC. (US) 2025-01-02 WO claimed
CN-119080856-A Mutant tRNA for codon extension 中外制药株式会社 2024-12-06 CN claimed
EP-4314000-A1 SYNTHESIS OF TRINUCLEOTIDE AND TETRANUCLEOTIDE CAPS FOR MRNA PRODUCTION ModernaTX, Inc. (US) 2024-02-07 EP claimed
CN-220176067-U A thick cauldron that evaporates for preparing bis (trimethylsilyl) acetamide 河南永源化工原料有限公司 2023-12-15 CN claimed
US-20230287032-A1 SYNTHESIS OF FLUORINATED NUCLEOTIDES MERCK SHARP & DOHME LLC (US) 2023-09-14 US claimed
EP-4196131-A1 SYNTHESIS OF FLUORINATED NUCLEOTIDES Merck Sharp & Dohme LLC (US) 2023-06-21 EP claimed
CN-114085218-A Coumarin two-photon initiator and synthesis method and application thereof 浙江大学 2022-02-25 CN claimed
WO-2022035917-A1 SYNTHESIS OF FLUORINATED NUCLEOTIDES MERCK SHARP & DOHME CORP. (US) 2022-02-17 WO claimed
EP-0065270-A2 Process for the preparation of 7-(2-amino-2-phenylacetamido)cephem derivatives and their use for the preparation of antibacterial agents Eisai Co., Ltd. (JP) 1982-11-24 EP claimed
US-4355172-A Process for 4-(D-3-amino-3-carboxypropoxy)-phenylglyoxylic acid oxime derivatives ELI LILLY AND COMPANY (US) 1982-10-19 US claimed
US-4337206-A Process for preparing high purity ursodeoxycholic acid ERREGIERRE S.P.A. (IT) 1982-06-29 US claimed
US-4316848-A Process for the purification of ursodeoxycholic acid BLASINACHIM S.P.A (IT) 1982-02-23 US claimed
US-4173569-A Preparation of pyrrolidine and pyrrolidin-2-one derivatives I.S.F. SPA (IT) 1979-11-06 US claimed
US-4124594-A REACTING AMINO-HYDROXYBUTYRIC ACID WITH A SILYLATING AGENT FOLLOWED BY REACTION WITH A HALOGENATED ESTER, CYCLIZATION I.S.F. SPA (IT) 1978-11-07 US claimed
US-4072710-A FROM SILYL ESTER AND THIONYL CHLORIDE PALOMO COLL A L 1978-02-07 US claimed
US-4029883-A Dehydroxylation of aminosugars TAKEDA CHEMICAL INDUSTRIES, LTD. (JA) 1977-06-14 US claimed
US-4020269-A Epiminodeaminodeoxyaminoglycoside antibiotics and intermediates TAKEDA CHEMICAL INDUSTRIES, LTD. (JA) 1977-04-26 US claimed
US-3956179-A STATIONARY PHASE COMPONENT FOR CATALYSIS OR CHROMATOGRAPHY Helsaz, Istvan (DT) 1976-05-11 US claimed