SCHEMBL4746690

SCHEMBL4746690

C=C(C(N)=O)C([Si](C)(C)C)[Si](C)(C)C

nearest known ligand 0.41

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7266017 0.76 GRIK1 (0.31)
SCHEMBL11649436 0.73 TDP1 (0.36) TDP1
SCHEMBL886929 0.72
SCHEMBL222605 0.71 LMNA (0.35) TDP1
Hydrochloric Acid SCHEMBL22189250 0.70
SCHEMBL15071 0.69
SCHEMBL3586576 0.69 LMNA (0.33)
SCHEMBL7187887 0.69 TDP1 (0.47) TDP1
SCHEMBL1486033 0.68 SLC7A5 (0.42) TDP1
SCHEMBL22551738 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008103593-A1 POWDER COATING FLUOROPOLYMER COMPOSITIONS WITH DEPROTECTABLE AROMATIC MATERIALS 3M INNOVATIVE PROPERTIES COMPANY (US) 2008-08-28 WO disclosed
US-4647681-A Method for the preparation of persilylated carboxylic acid amides DYNAMIT NOBEL AG (DE) 1987-03-03 US disclosed
US-4609749-A Method for the simultaneous preparation of carboxylic acid trimethylsilyl esters and silylated carboxylic acid amides DYNAMIT NOBEL AG (DE) 1986-09-02 US disclosed
US-4105648-A CROSSLINKED POLYACRYLAMIDES CONTAINING SILYL GROUPS CIBA-GEIGY CORPORATION (US) 1978-08-08 US disclosed