Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 9/20 | 0.46 |
| ▸ | NTMT1 | Q9BV86 | 2/20 | 0.45 |
| ▸ | ACE | P12821 | 3/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 6/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 6/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 6/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7053068 | 0.88 | F2 (0.43) | F2NTMT1ACEMMP2MMP9 | |
| SCHEMBL2226082 | 0.88 | DPP4 (0.46) | F2PRSS1PRSS2PRSS3DPP4 | |
| SCHEMBL12955380 | 0.85 | DPP4 (0.42) | F2PRSS1PRSS2PRSS3DPP4 | |
| SCHEMBL9603823 | 0.85 | DPP4 (0.44) | F2PRSS1PRSS2PRSS3DPP4 | |
| SCHEMBL263537 | 0.85 | PDF (0.46) | F2NTMT1MMP2MMP9PRSS1 | |
| SCHEMBL29427848 | 0.85 | PDF (0.46) | F2NTMT1MMP2MMP9PRSS1 | |
| Acetic Acid SCHEMBL16234756 | 0.84 | PDF (0.44) | F2NTMT1ACEPRSS1PRSS2 | |
| SCHEMBL6712279 | 0.83 | ITGB1 (0.55) | TSHR | |
| SCHEMBL29582281 | 0.82 | F2 (0.56) | F2NTMT1ACEOPRM1 | |
| SCHEMBL14336163 | 0.82 | DPP4 (0.45) | F2OPRM1PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022235952-A1 | METHODS FOR DIAGNOSIS AND TREAMENT OF CHRONIC PROSTATITIS AND/OR CHRONIC PELVIC PAIN SYNDROME | NORTHWESTERN UNIVERSITY (US) | 2022-11-10 | — | — | WO | disclosed |
| WO-2010059372-A2 | TRYPTASE ENZYME INHIBITING AMINOPYRIDINES | HERBALSCIENCE GROUP, LLC (US) | 2010-05-27 | — | — | WO | disclosed |
| WO-2010053902-A2 | TRYPTASE ENZYME INHIBITING AMINOTHIOPHENOLS | HERBALSCIENCE GROUP, LLC (US) | 2010-05-14 | — | — | WO | disclosed |
| WO-2010009091-A2 | ANTI-INFLAMMATORY AND ANTI-ALLERGY EXTRACTS FROM NETTLE | HERBALSCIENCE GROUP, LLC (US) | 2010-01-21 | — | — | WO | disclosed |
| EP-1150979-A1 | HETEROARYL AMIDINES, METHYLAMIDINES AND GUANIDINES AS PROTEASE INHIBITORS | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 2001-11-07 | — | — | EP | disclosed |
| EP-1036063-A1 | HETEROARYL AMINOGUANIDINES AND ALKOXYGUANIDINES AND THEIR USE AS PROTEASE INHIBITORS | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 2000-09-20 | — | — | EP | disclosed |
| WO-2000047578-A1 | HETEROARYL AMIDINES, METHYLAMIDINES AND GUANIDINES AS PROTEASE INHIBITORS | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 2000-08-17 | — | — | WO | disclosed |
| WO-1999026926-A1 | HETEROARYL AMINOGUANIDINES AND ALKOXYGUANIDINES AND THEIR USE AS PROTEASE INHIBITORS | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 1999-06-03 | — | — | WO | disclosed |
| WO-1997047299-A1 | AMIDINO AND GUANIDINO HETEROCYCLIC PROTEASE INHIBITORS | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 1997-12-18 | — | — | WO | disclosed |
| WO-1995011298-A1 | PORPHYROMONAS GINGIVALIS LYSINE-SPECIFIC PROTEINASE | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 1995-04-27 | — | — | WO | disclosed |