Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 11/20 | 0.42 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.40 |
| ▸ | ANO1 | Q5XXA6 | 3/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | CTSA | P10619 | 1/20 | 0.35 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19205583 | 1.00 | RORC (0.42) | RORCRIPK1ANO1HDAC6CTSA | |
| SCHEMBL21796351 | 0.88 | TRPV1 (0.40) | RORCRIPK1ANO1 | |
| SCHEMBL19205763 | 0.88 | TRPV1 (0.40) | RORCRIPK1ANO1 | |
| SCHEMBL21796350 | 0.85 | RIPK1 (0.40) | RORCRIPK1NTRK1TP53 | |
| SCHEMBL19205749 | 0.85 | RIPK1 (0.40) | RORCRIPK1NTRK1TP53 | |
| SCHEMBL19205594 | 0.79 | KCNJ5 (0.42) | RORCNTRK1 | |
| SCHEMBL19205595 | 0.79 | KCNJ5 (0.42) | RORCNTRK1 | |
| SCHEMBL18449666 | 0.77 | RORC (0.44) | RORC | |
| SCHEMBL18448522 | 0.77 | RORC (0.46) | RORCANO1 | |
| SCHEMBL21796352 | 0.76 | RORC (0.44) | RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3686187-A1 | PROCESS FOR THE PREPARATION OF ROR GAMMA MODULATORS | Glenmark Pharmaceuticals S.A. (CH) | 2020-07-29 | — | — | EP | disclosed |