Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 4/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | HTR1D | P28221 | 1/20 | 0.37 |
| ▸ | HTR1B | P28222 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20917818 | 0.91 | KMT2A (0.46) | CYP1A2CYP2D6TSHRSIGMAR1L3MBTL1 | |
| SCHEMBL20917965 | 0.81 | MAPK1 (0.41) | CYP1A2CYP2D6TSHRSIGMAR1L3MBTL1 | |
| SCHEMBL22263103 | 0.81 | KMT2A (0.47) | CYP1A2CYP2D6TSHRSIGMAR1KMT2A | |
| SCHEMBL22263137 | 0.80 | MAPK1 (0.50) | CYP1A2CYP2D6TSHRSIGMAR1MAPK1 | |
| SCHEMBL20918028 | 0.79 | CYP1A2 (0.44) | CYP1A2CYP2D6TSHRSIGMAR1L3MBTL1 | |
| SCHEMBL19061440 | 0.78 | MAPK1 (0.46) | SIGMAR1MAPK1LMNAALDH1A1HTT | |
| SCHEMBL19061872 | 0.77 | MAPK1 (0.41) | CYP1A2CYP2D6TSHRSIGMAR1L3MBTL1 | |
| SCHEMBL19061597 | 0.77 | KDM4E (0.41) | CYP1A2CYP2D6TSHRSIGMAR1MAPK1 | |
| SCHEMBL19019834 | 0.76 | PLA2G7 (0.47) | CYP1A2CYP2D6MAPK1KMT2AMEN1 | |
| SCHEMBL22275730 | 0.76 | ALDH1A1 (0.51) | CYP1A2CYP2D6TSHRSIGMAR1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200239452-A1 | IDO/TDO Inhibitor | CANBAS CO., LTD. (JP) | 2020-07-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200239452-A1 | IDO/TDO Inhibitor | IDO1, IDO2, TDO2 | CYP1A2 363/4885CYP2D6 575/4885TSHR 115/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.