SCHEMBL22264064

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL29632027	1.00	AR (0.70)	ARNPC1RAB9ACYP1B1EGFR
	SCHEMBL25197758	0.86	SRD5A2 (0.59)	ARNPC1RAB9ACYP1B1CXCL12
	SCHEMBL25199493	0.86	SRD5A2 (0.59)	ARNPC1RAB9ACYP1B1CXCL12
	SCHEMBL25202088	0.86	AR (0.78)	ARNPC1RAB9ACYP1B1MAOB
	SCHEMBL25266016	0.86	AR (0.78)	ARNPC1RAB9ACYP1B1MAOB
	SCHEMBL30384316	0.86	AR (0.78)	ARNPC1RAB9ACYP1B1MAOB
	SCHEMBL25198960	0.86	AR (0.73)	ARCXCL12MAOBHDAC4HDAC1
	SCHEMBL25219942	0.85	CXCL12 (0.63)	ARCYP1B1CXCL12MAOBMAPT
	SCHEMBL27890333	0.84	MAPT (0.67)	ARCYP1B1MAOBMAPTMAOA
	SCHEMBL8987373	0.83	PTGS1 (0.67)	ARCYP1B1EGFRCXCL12MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.