Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALM1 | P0DP23 | 1/20 | 0.39 |
| ▸ | BCL2 | P10415 | 1/20 | 0.38 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.38 |
| ▸ | IDH1 | O75874 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | FUCA1 | P04066 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18890767 | 0.66 | CALM1 (0.38) | CALM1BCL2BCL2L1IDH1MEN1 | |
| SCHEMBL31503053 | 0.66 | CALM1 (0.38) | CALM1MEN1KMT2AHPGDUSP2 | |
| Diphenylmethane SCHEMBL10394702 | 0.64 | CALM1 (0.92) | CALM1BCL2BCL2L1IDH1ALDH1A1 | |
| Diphenylmethane SCHEMBL7400899 | 0.63 | CALM1 (0.57) | CALM1BCL2BCL2L1IDH1 | |
| SCHEMBL1829354 | 0.62 | CALM1 (0.55) | CALM1BCL2BCL2L1HPGDUSP2 | |
| SCHEMBL2045801 | 0.62 | CALM1 (0.55) | CALM1IDH1 | |
| SCHEMBL7752320 | 0.62 | IDH1 (0.42) | CALM1BCL2BCL2L1IDH1ALOX5 | |
| Diphenylmethane SCHEMBL4361124 | 0.61 | CALM1 (1.00) | CALM1BCL2BCL2L1IDH1HPGD | |
| Diphenylmethane SCHEMBL14763944 | 0.61 | CALM1 (1.00) | CALM1BCL2BCL2L1IDH1HPGD | |
| Diphenylmethane SCHEMBL3792579 | 0.61 | CALM1 (1.00) | CALM1BCL2BCL2L1IDH1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3038612-B1 | CYCLIC VINYLOGOUS AMIDES AS BROMODOMAIN INHIBITORS | ICAHN SCHOOL MED MOUNT SINAI (US) | 2020-07-29 | — | — | EP | disclosed |