Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALM1 | P0DP23 | 1/20 | 0.38 |
| ▸ | FUCA1 | P04066 | 3/20 | 0.36 |
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | IDH1 | O75874 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | SLC5A2 | P31639 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | BCL2 | P10415 | 1/20 | 0.33 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.33 |
| ▸ | GBA1 | P04062 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22268641 | 0.66 | CALM1 (0.39) | CALM1FUCA1IDH1MEN1KMT2A | |
| SCHEMBL31503053 | 0.64 | CALM1 (0.38) | CALM1LMNAMEN1KMT2A | |
| SCHEMBL2352229 | 0.63 | CALM1 (0.52) | CALM1MAPTLMNATAAR1BCL2 | |
| Diphenylmethane SCHEMBL10394702 | 0.63 | CALM1 (0.92) | CALM1IDH1LMNABCL2BCL2L1 | |
| Diphenylmethane SCHEMBL7400899 | 0.62 | CALM1 (0.57) | CALM1IDH1LMNABCL2BCL2L1 | |
| Diphenylmethane SCHEMBL27450549 | 0.61 | CALM1 (0.86) | CALM1MAPTIDH1LMNATAAR1 | |
| SCHEMBL3690826 | 0.60 | CALM1 (0.42) | CALM1MAPTIDH1LMNATAAR1 | |
| SCHEMBL19667974 | 0.60 | CALM1 (0.42) | CALM1MAPTKMT2A | |
| Diphenylmethane SCHEMBL14763944 | 0.60 | CALM1 (1.00) | CALM1MAPTIDH1LMNABCL2 | |
| Diphenylmethane SCHEMBL4361124 | 0.60 | CALM1 (1.00) | CALM1MAPTIDH1LMNABCL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2561080-B1 | A NEW KANAMYCIN COMPOUND, KANAMYCIN-PRODUCING STREPTOMYCES SPECIES BACTERIUM, AND METHOD OF PRODUCING KANAMYCIN | INTRON BIOTECHNOLOGY INC (KR) | 2017-05-24 | — | — | EP | disclosed |