Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 4/20 | 0.35 |
| ▸ | LCK | P06239 | 3/20 | 0.35 |
| ▸ | FLT1 | P17948 | 3/20 | 0.35 |
| ▸ | FLT4 | P35916 | 3/20 | 0.35 |
| ▸ | FLT3 | P36888 | 3/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.35 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.35 |
| ▸ | AXL | P30530 | 2/20 | 0.35 |
| ▸ | FRK | P42685 | 2/20 | 0.35 |
| ▸ | CLK2 | P49760 | 2/20 | 0.35 |
| ▸ | BLK | P51451 | 2/20 | 0.35 |
| ▸ | CSNK1G2 | P78368 | 2/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.35 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.35 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.35 |
| ▸ | CSNK1G1 | Q9HCP0 | 2/20 | 0.35 |
| ▸ | MAP4K5 | Q9Y4K4 | 2/20 | 0.35 |
| ▸ | CSNK1G3 | Q9Y6M4 | 2/20 | 0.35 |
| ▸ | CDK1 | P06493 | 1/20 | 0.35 |
| ▸ | ITK | Q08881 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22270835 | 0.79 | KDR (0.42) | KDRMAPTSMN1; SMN2NPC1TP53 | |
| SCHEMBL18448521 | 0.76 | RORC (0.49) | RORCSMN1; SMN2GAARAB9AWNT3A | |
| SCHEMBL22270870 | 0.74 | TRPV1 (0.42) | MAPTSMN1; SMN2GAARAB9ATRPV1 | |
| SCHEMBL22271066 | 0.74 | RORC (0.35) | RORCMAPT | |
| SCHEMBL22271074 | 0.74 | CA12 (0.37) | SMN1; SMN2GAANPC1TP53PKM | |
| SCHEMBL22270863 | 0.74 | GSK3B (0.38) | LCKFLT3MAP4K4ROCK1AURKB | |
| SCHEMBL22271057 | 0.73 | TRPV1 (0.43) | RORCSMN1; SMN2GAANPC1RAB9A | |
| SCHEMBL22270537 | 0.71 | MAPT (0.36) | KDRMAPTSMN1; SMN2GAANPC1 | |
| SCHEMBL10980866 | 0.70 | RARB (0.49) | HDAC1MAPTSMN1; SMN2KDM1ANPC1 | |
| SCHEMBL15451320 | 0.69 | RARB (0.48) | HDAC1SMN1; SMN2KDM1ANPC1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3686187-A1 | PROCESS FOR THE PREPARATION OF ROR GAMMA MODULATORS | Glenmark Pharmaceuticals S.A. (CH) | 2020-07-29 | — | — | EP | disclosed |