Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 3/20 | 0.35 |
| ▸ | CNR1 | P21554 | 5/20 | 0.33 |
| ▸ | CNR2 | P34972 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | ACP1 | P24666 | 1/20 | 0.31 |
| ▸ | MME | P08473 | 2/20 | 0.31 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | NAMPT | P43490 | 1/20 | 0.30 |
| ▸ | GCGR | P47871 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22270537 | 0.87 | MAPT (0.36) | MAPT | |
| SCHEMBL22270563 | 0.82 | WNT3A (0.39) | RORCMAPT | |
| SCHEMBL22270880 | 0.80 | LMNA (0.37) | MAPTNAMPT | |
| SCHEMBL22270887 | 0.78 | KDM4E (0.40) | MAPTMCHR1 | |
| SCHEMBL22270886 | 0.77 | L3MBTL1 (0.35) | MAPT | |
| SCHEMBL22271073 | 0.76 | CCR1 (0.32) | — | |
| SCHEMBL22270885 | 0.75 | RORC (0.35) | RORCMAPT | |
| SCHEMBL22270626 | 0.74 | KDR (0.35) | RORCMAPT | |
| SCHEMBL19205766 | 0.73 | RORC (0.48) | RORCMAPT | |
| SCHEMBL22271071 | 0.71 | CNR1 (0.39) | CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3686187-A1 | PROCESS FOR THE PREPARATION OF ROR GAMMA MODULATORS | Glenmark Pharmaceuticals S.A. (CH) | 2020-07-29 | — | — | EP | disclosed |