Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22270563 | 0.89 | WNT3A (0.39) | MAPTMEN1KMT2APDE10AKDR | |
| SCHEMBL22271066 | 0.87 | RORC (0.35) | MAPT | |
| SCHEMBL22270880 | 0.82 | LMNA (0.37) | MAPTMEN1ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL18485956 | 0.79 | WNT3A (0.35) | MAPTMEN1ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL22270885 | 0.78 | RORC (0.35) | MAPTALDH1A1SMN1; SMN2PDE10AKDR | |
| SCHEMBL22270867 | 0.78 | WNT3A (0.32) | MAPTSMN1; SMN2TRPV1LMNAWNT3A | |
| SCHEMBL22270671 | 0.78 | RORC (0.39) | SMN1; SMN2PDE10AKDRWNT3A | |
| SCHEMBL22270668 | 0.78 | KDR (0.36) | MAPTMEN1ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL22271062 | 0.75 | LPAR1 (0.35) | KDR | |
| SCHEMBL22271048 | 0.75 | PDGFRB (0.41) | MAPTALDH1A1SMN1; SMN2LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3686187-A1 | PROCESS FOR THE PREPARATION OF ROR GAMMA MODULATORS | Glenmark Pharmaceuticals S.A. (CH) | 2020-07-29 | — | — | EP | disclosed |