SCHEMBL22272475

SCHEMBL22272475

CCC(C)(CC)[C@H]1OC(C(=O)O)C(O)C(OC2OC(C(=O)O)C(OC)C(O)C2O)C1NC(C)=O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ BDNF P23560 3/20 0.40
▸ PTN P21246 2/20 0.40
▸ MDK P21741 2/20 0.40
▸ F10 P00742 2/20 0.35
▸ LGALS3 P17931 7/20 0.35
▸ LGALS8 O00214 1/20 0.35
▸ LGALS4 P56470 1/20 0.35
▸ LGALS7; LGALS7B P47929 2/20 0.33
▸ LGALS1 P09382 1/20 0.33
▸ HPSE Q9Y251 2/20 0.32
▸ LGALS9 O00182 2/20 0.32
▸ FGF1 P05230 1/20 0.32
▸ BMP2 P12643 2/20 0.32
▸ VEGFA P15692 2/20 0.32
▸ CXCL12 P48061 2/20 0.32
▸ SHH Q15465 2/20 0.32
▸ IFNG P01579 1/20 0.32
▸ PF4 P02776 1/20 0.32
▸ CCL2 P13500 1/20 0.32
▸ SELP P16109 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18936352 0.91 LGALS3 (0.43) BDNFPTNMDKLGALS3LGALS8
SCHEMBL19325099 0.91 LGALS3 (0.43) BDNFPTNMDKLGALS3LGALS8
SCHEMBL21908706 0.86 LGALS3 (0.41) BDNFPTNMDKLGALS3LGALS8
SCHEMBL16248154 0.83 BDNF (0.45) BDNFPTNMDKF10LGALS3
SCHEMBL16884736 0.83 BDNF (0.45) BDNFPTNMDKF10LGALS3
SCHEMBL20290392 0.82 LGALS3 (0.42) BDNFPTNMDKLGALS3LGALS8
SCHEMBL21316642 0.81 LGALS3 (0.42) BDNFPTNMDKLGALS3LGALS8
SCHEMBL22472735 0.81 LGALS3 (0.42) BDNFPTNMDKLGALS3LGALS8
SCHEMBL18737220 0.81 LGALS3 (0.42) BDNFPTNMDKLGALS3LGALS8
SCHEMBL20122304 0.81 LGALS3 (0.42) BDNFPTNMDKLGALS3LGALS8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11229656-B2 Hyaluronan conjugates with pharmaceutically active substances, methods and compositions SYNARTRO AB (SE) 2022-01-25 — — US disclosed
US-20200237783-A1 HYALURONAN CONJUGATES WITH PHARMACEUTICALLY ACTIVE SUBSTANCES, METHODS AND COMPOSITIONS SYNARTRO AB (SE) 2020-07-30 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200237783-A1 HYALURONAN CONJUGATES WITH PHARMACEUTICALLY ACTIVE SUBSTANCES, METHODS AND COMPOSITIONS CD44, PIGS, HPSE BDNF 1078/4885PTN 475/4885MDK 604/4885
US-11229656-B2 Hyaluronan conjugates with pharmaceutically active substances, methods and compositions CD44, PIGS, HPSE BDNF 1078/4885PTN 475/4885MDK 604/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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