SCHEMBL18936352

SCHEMBL18936352

CCC(C)(CC)C1OC(CO)C(O)C(OC2OC(C(=O)O)C(OC)C(O)C2O)C1NC(C)=O

nearest known ligand 0.43

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ LGALS3 P17931 7/20 0.43
▸ LGALS8 O00214 1/20 0.43
▸ LGALS4 P56470 1/20 0.43
▸ MAPK1 P28482 2/20 0.41
▸ MDK P21741 3/20 0.41
▸ BDNF P23560 3/20 0.41
▸ PTN P21246 2/20 0.41
▸ LGALS7; LGALS7B P47929 2/20 0.40
▸ LGALS1 P09382 1/20 0.40
▸ LGALS9 O00182 2/20 0.39
▸ ALDH1A1 P00352 1/20 0.39
▸ THRB P10828 1/20 0.39
▸ CD69 Q07108 1/20 0.39
▸ CHIA Q9BZP6 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19325099 1.00 LGALS3 (0.43) LGALS3LGALS8LGALS4MAPK1MDK
SCHEMBL21908706 0.94 LGALS3 (0.41) LGALS3LGALS8LGALS4MAPK1MDK
SCHEMBL20290392 0.91 LGALS3 (0.42) LGALS3LGALS8LGALS4MAPK1MDK
SCHEMBL18608138 0.91 LGALS3 (0.43) LGALS3LGALS8LGALS4MAPK1MDK
SCHEMBL18608226 0.91 LGALS3 (0.43) LGALS3LGALS8LGALS4MAPK1MDK
SCHEMBL23322444 0.91 LGALS3 (0.43) LGALS3LGALS8LGALS4MAPK1MDK
SCHEMBL22272475 0.91 BDNF (0.40) LGALS3LGALS8LGALS4MDKBDNF
SCHEMBL21316642 0.90 LGALS3 (0.42) LGALS3LGALS8LGALS4MAPK1MDK
SCHEMBL22472735 0.90 LGALS3 (0.42) LGALS3LGALS8LGALS4MAPK1MDK
SCHEMBL18737220 0.90 LGALS3 (0.42) LGALS3LGALS8LGALS4MAPK1MDK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11311472-B2 Topical composition comprising crosslinked hyaluronic acid and a polyacrylate compound TEOXANE (CH) 2022-04-26 — — US disclosed
US-11091566-B2 Methods for the production of biopolymers with defined average molecular weight MEDSKIN SOLUTIONS DR. SUWELACK AG (DE) 2021-08-17 — — US disclosed
US-20210244644-A1 TOPICAL COMPOSITION COMPRISING CROSSLINKED HYALURONIC ACID AND A POLYACRYLATE COMPOUND TEOXANE (CH) 2021-08-12 — — US disclosed
US-10976324-B2 Synergistic combination of biomarkers for detecting and assessing hepatic fibrosis UNIVERSITÉ PARIS CITÉ (FR) 2021-04-13 — — US disclosed
US-20210052477-A1 TOPICAL SKIN COMPOSITIONS FOR TREATING WRINKLES ALLUSTRA TECHNOLOGIES LLC 2021-02-25 — — US disclosed
US-10632081-B2 Intralymphatic delivery of hyaluronan nanoparticle for cancer metastasis INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2020-04-28 — — US disclosed
US-20180078490-A1 TOPICAL SKIN COMPOSITIONS FOR TREATING WRINKLES ALLUSTRA TECHNOLOGIES LLC 2018-03-22 — — US disclosed
US-20170160289-A1 SYNERGISTIC COMBINATION OF BIOMARKERS FOR DETECTING AND ASSESSING HEPATIC FIBROSIS BIO-RAD INNOVATIONS (FR) 2017-06-08 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180078490-A1 TOPICAL SKIN COMPOSITIONS FOR TREATING WRINKLES CUTA, FABP4, PLOD3 LGALS3 1148/4885LGALS8 2792/4885LGALS4 807/4885
US-20210244644-A1 TOPICAL COMPOSITION COMPRISING CROSSLINKED HYALURONIC ACID AND A POLYACRYLATE COMPOUND CUTA, CD44, COL14A1 LGALS3 466/4885LGALS8 808/4885LGALS4 387/4885
US-10632081-B2 Intralymphatic delivery of hyaluronan nanoparticle for cancer metastasis DLST, CD44, DACH1 LGALS3 1138/4885LGALS8 2104/4885LGALS4 1374/4885
US-20210052477-A1 TOPICAL SKIN COMPOSITIONS FOR TREATING WRINKLES CUTA, COL14A1, GLA LGALS3 631/4885LGALS8 1236/4885LGALS4 498/4885
US-11091566-B2 Methods for the production of biopolymers with defined average molecular weight ALG1, MGAM, LGALS3 LGALS3 3/4885LGALS8 30/4885LGALS4 4/4885
US-11311472-B2 Topical composition comprising crosslinked hyaluronic acid and a polyacrylate compound CUTA, CD44, COL14A1 LGALS3 466/4885LGALS8 808/4885LGALS4 387/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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