Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.36 |
| ▸ | F10 | P00742 | 4/20 | 0.36 |
| ▸ | FASN | P49327 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.36 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | PORCN | Q9H237 | 1/20 | 0.35 |
| ▸ | IKBKB | O14920 | 1/20 | 0.35 |
| ▸ | CHUK | O15111 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2229360 | 0.98 | MMP2 (0.43) | MMP2MMP9MRGPRX4GRIN2BF10 | |
| SCHEMBL2228696 | 0.91 | MMP2 (0.48) | MMP2MMP9GRIN2B | |
| SCHEMBL2228990 | 0.89 | MMP2 (0.46) | MMP2MMP9GRIN2B | |
| SCHEMBL2228470 | 0.89 | MMP2 (0.47) | MMP2MMP9GRIN2BF10 | |
| SCHEMBL2227262 | 0.89 | MMP2 (0.41) | MMP2MMP9MRGPRX4GRIN2BCYP3A4 | |
| SCHEMBL2228462 | 0.86 | MMP2 (0.40) | MMP2MMP9GRIN2BCYP3A4CYP2D6 | |
| SCHEMBL2228689 | 0.84 | MMP2 (0.43) | MMP2MMP9GRIN2B | |
| SCHEMBL2229023 | 0.82 | MMP2 (0.45) | MMP2MMP9GRIN2B | |
| SCHEMBL2228670 | 0.82 | MMP2 (0.45) | MMP2MMP9GRIN2BFASN | |
| SCHEMBL2362512 | 0.80 | MMP2 (0.43) | MMP2MMP9GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011089550-A1 | ALKYL-HETEROCYCLE CARBAMATE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION | SANOFI AVENTIS (FR) | 2011-07-28 | — | — | WO | disclosed |