Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.45 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 3/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | TNF | P01375 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.35 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.34 |
| ▸ | GALR3 | O60755 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2228670 | 0.90 | MMP2 (0.45) | MMP2MMP9GRIN2BKDM4ETNF | |
| SCHEMBL2228696 | 0.89 | MMP2 (0.48) | MMP2MMP9GRIN2BKDM4ETNF | |
| SCHEMBL2228689 | 0.87 | MMP2 (0.43) | MMP2MMP9GRM5F2MGLL | |
| SCHEMBL2228470 | 0.85 | MMP2 (0.47) | MMP2MMP9GRIN2BKDM4EENPP2 | |
| SCHEMBL2228990 | 0.84 | MMP2 (0.46) | MMP2MMP9GRIN2BKDM4EENPP2 | |
| SCHEMBL2227124 | 0.83 | MMP2 (0.44) | MMP2MMP9GRM5F2GRIN2B | |
| SCHEMBL2229360 | 0.82 | MMP2 (0.43) | MMP2MMP9GRIN2B | |
| SCHEMBL2227253 | 0.82 | MMP2 (0.43) | MMP2MMP9GRIN2B | |
| SCHEMBL2286530 | 0.80 | MMP2 (0.41) | MMP2MMP9MGLLGRIN2B | |
| SCHEMBL2358210 | 0.80 | F2 (0.43) | F2GRIN2BKDM4ETNFLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011089550-A1 | ALKYL-HETEROCYCLE CARBAMATE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION | SANOFI AVENTIS (FR) | 2011-07-28 | — | — | WO | disclosed |