Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.38 |
| ▸ | NOS3 | P29474 | 1/20 | 0.38 |
| ▸ | NOS1 | P29475 | 1/20 | 0.38 |
| ▸ | NOS2 | P35228 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2228470 | 0.98 | MMP2 (0.47) | MMP2MMP9GRIN2BKDM4EALDH1A1 | |
| SCHEMBL2228696 | 0.93 | MMP2 (0.48) | MMP2MMP9GRIN2BKDM4ENPC1 | |
| SCHEMBL2227253 | 0.89 | MMP2 (0.43) | MMP2MMP9GRIN2B | |
| SCHEMBL2229024 | 0.88 | GRIN2B (0.42) | MMP2MMP9GRIN2BKDM4EALDH1A1 | |
| SCHEMBL2229360 | 0.88 | MMP2 (0.43) | MMP2MMP9GRIN2B | |
| SCHEMBL2227230 | 0.86 | GRIN2B (0.44) | MMP2MMP9GRIN2BKDM4EALDH1A1 | |
| SCHEMBL2228689 | 0.85 | MMP2 (0.43) | MMP2MMP9GRIN2BENPP2MEN1 | |
| SCHEMBL2229023 | 0.84 | MMP2 (0.45) | MMP2MMP9GRIN2BKDM4EENPP2 | |
| SCHEMBL2228670 | 0.84 | MMP2 (0.45) | MMP2MMP9GRIN2BKDM4E | |
| SCHEMBL2362512 | 0.81 | MMP2 (0.43) | MMP2MMP9GRIN2BMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011089550-A1 | ALKYL-HETEROCYCLE CARBAMATE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION | SANOFI AVENTIS (FR) | 2011-07-28 | — | — | WO | disclosed |